Evidence map›Paper›PMID 28957949›Full record

ReviewClinical obstetrics and gynecology2017

Ovarian Cancer Prevention in High-risk Women.

Sarah M Temkin, Jennifer Bergstrom, Goli Samimi, Lori Minasian

Open access · greenAbstract readReview
In one paragraph

Review in Clinical obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Systematic mapping review of guidelines forInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Pooled it
  2. Endometriosis and autoimmunity.Autoimmunity reviews · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. The Role of Statins in the Prevention of Ovarian and Endometrial Cancers.Cancer prevention research (Philadelphia, Pa.) · 2023
    Article
  7. Hereditary Ovarian Cancer: Towards a Cost-Effective Prevention Strategy.International journal of environmental research and public health · 2022
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sarah M Temkin*Department of Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, Virginia †Johns Hopkins School of Medicine, Kelly Gynecologic Oncology Service, Baltimore, Maryland ‡Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland.
Jennifer Bergstrom
Goli Samimi
Lori Minasian
National Cancer Institute · USJohns Hopkins University · USVirginia Commonwealth University · US

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Ovarian carcinoma is the most lethal malignancy of the female genital tract. Population-based trials in the general population have not demonstrated that screening improves early detection or survival. Therefore, application of prevention strategies is vital to improving outcomes from this disease. Surgical prevention reduces risk and prophylactic risk-reducing salpingo-oophorectomy is the most effective means to prevent ovarian carcinoma in the high-risk patient although the risks do not outweigh the benefits in average risk patients. Other surgical and medical options have unknown or limited efficacy in the high-risk patient. In this review, we define the patient at high risk for ovarian cancer, discuss how to identify these women and weigh their available ovarian cancer prevention strategies.

Indexed as

AdultCarcinomaEarly Detection of CancerFemaleGenes, BRCA1Genes, BRCA2Genetic TestingGerm-Line MutationHumansMiddle AgedOvarian NeoplasmsProphylactic Surgical ProceduresRisk AssessmentRisk Factors

Identifiers

PMID28957949
PMCPMC5920567
OpenAlexW2758700018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.