Evidence map›Paper›PMID 28957718›Full record

ArticleJournal of pharmaceutical and biomedical analysis2018

Accurate quantification of PGE

Changhong Yun, Wan-Mohaiza Dashwood, Lawrence N Kwong, Song Gao, Taijun Yin, Qinglan Ling, Rashim Singh, Roderick H Dashwood, Ming Hu

Abstract read
In one paragraph

Article in Journal of pharmaceutical and biomedical analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Changhong YunDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, 1441 Moursund St., Houston, TX, 77030, USA.
Wan-Mohaiza DashwoodCenter for Epigenetics & Disease Prevention, Texas A&M College of Medicine, 2121 W. Holcombe Blvd., Houston, TX, 77030, USA.
Lawrence N KwongDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Song GaoDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, 1441 Moursund St., Houston, TX, 77030, USA.
Taijun YinDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, 1441 Moursund St., Houston, TX, 77030, USA.
Qinglan LingDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, 1441 Moursund St., Houston, TX, 77030, USA.
Rashim SinghDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, 1441 Moursund St., Houston, TX, 77030, USA.
Roderick H DashwoodCenter for Epigenetics & Disease Prevention, Texas A&M College of Medicine, 2121 W. Holcombe Blvd., Houston, TX, 77030, USA. Electronic address: rdashwood@ibt.tamhsc.edu.
Ming HuDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, 1441 Moursund St., Houston, TX, 77030, USA. Electronic address: mhu@uh.edu.
University of Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Dietary HDAC Inhibitors in Colon Cancer PreventionR01CA122959 · NCI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI DASHWOOD, RODERICK H · 2008 to 2023
$4.3M
Disposition of Flavonoids via Metabolic InterplayR01GM070737 · NIGMS · UNIVERSITY OF HOUSTON · PI HU, MING · 2006 to 2017
$3.7M
Developing Recycled Colon Bioavailable (r-CB) COXIBs for the Treatment of Familial adenomatous polyposis (FAP)R03CA212937 · NCI · UNIVERSITY OF HOUSTON · PI GAO, SONG · 2017 to 2018
$152k
NCI NIH HHS R01 CA122959NCI NIH HHS R03 CA212937NIGMS NIH HHS R01 GM070737
6 · The paper itself

Abstract

An accurate and reliable UPLC-MS/MS method is reported for the quantification of endogenous Prostaglandin E2 (PGE

Indexed as

AnimalsBiological AssayBiomarkersChromatography, High Pressure LiquidColonColorectal NeoplasmsDinoprostoneInflammationIsotope LabelingRatsReproducibility of ResultsSensitivity and SpecificityTandem Mass SpectrometryBiomarkersDinoprostoneColonCOX-2CRCEndogenous biomarkerFAPPGE(2)Pirc ratUPLC–MS/MS

Identifiers

PMID28957718
PMCPMC5698167
OpenAlexW2736843813

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.