Evidence map›Paper›PMID 28957553›Full record

ArticleRheumatology (Oxford, England)2017

Disease activity dynamics in rheumatoid arthritis: patients' self-assessment of disease activity via WebApp.

Ulrich A Walker, Ruediger B Mueller, Veronika K Jaeger, Robert Theiler, Adrian Forster, Patrick Dufner, Fabiana Ganz, Diego Kyburz

Abstract readEvaluation StudyMulticenter Study
In one paragraph

Article in Rheumatology (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ulrich A WalkerDepartment of Rheumatology, University Hospital Basel, Basel.
Ruediger B MuellerDivision of Rheumatology, Department of Internal Medicine, Kantonsspital St Gallen, St Gallen.
Veronika K JaegerDepartment of Rheumatology, University Hospital Basel, Basel.
Robert TheilerDepartment of Rheumatology, Triemli Hospital, Zurich.
Adrian ForsterDepartment of Rheumatology, Klinik St Katharinental, Diessenhofen.
Patrick DufnerAbbVie AG, Baar, Switzerland.
Fabiana GanzAbbVie AG, Baar, Switzerland.
Diego KyburzDepartment of Rheumatology, University Hospital Basel, Basel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim was to evaluate patient self-assessment of RA disease activity in terms of Routine Assessment of Patient Index Data (RAPID) scores via a Web-based smartphone application (WebApp). Methods: In this prospective, multicentre study, adult RA patients were examined by a rheumatologist at baseline and after 3 months. Patients were asked to complete WebApp questionnaires weekly. The time course of patient-assessed RAPID3/4 scores and their correlations with rheumatologist-assessed DAS28, as well as Clinical and Simplified Disease Activity Indices (CDAI/SDAI), were evaluated. Results: Eighty patients were included in the analysis (median RA duration, 4.5 years; age, 57 years; 59% female). At baseline, there was a moderate to strong correlation between RAPID3 and DAS28 (r = 0.63), CDAI (r = 0.65) and SDAI (r = 0.61) scores. Similar or stronger correlations were seen at the 3-month follow-up visit (DAS28 r = 0.66, CDAI r = 0.71 and SDAI r = 0.61). Similar correlations were seen between RAPID4 and rheumatologist assessments. Correlations were not influenced by demographics or RA treatment. In the 3-month period, the RAPID3 score changed into a higher severity category than the category at baseline at least once in 47% of patients. When DAS28 scores were predicted from the RAPID3, 11% of patients had an increase of > 1 DAS28 unit during the 3-month observation period. Conclusion: Web-based patient assessments were strongly correlated with rheumatologist assessments of RA activity and showed considerable variation during follow-up. This provides a rationale for further exploration of their use as cost-effective tools to monitor RA activity between outpatient visits and to optimize tight control strategies.

Indexed as

Diagnostic Self EvaluationMobile ApplicationsSeverity of Illness IndexAdultAgedArthritis, RheumatoidDisability EvaluationDisease ProgressionFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesReproducibility of ResultsSmartphonepatient-reported outcomepatient’s self-assessmentRAPID scorerheumatoid arthritistight control

Identifiers

PMID28957553
PMCPMC5873216

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.