ArticlePloS one2017
Colonoscopy reduces colorectal cancer mortality: A multicenter, long-term, colonoscopy-based cohort study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Precision Patient Navigation to Improve Rates of Follow-up Colonoscopy, An Individual Randomized Effectiveness Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Trial
- [Achievements and Future Directions of the National Colorectal Cancer Screening Program in Korea].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026Article
- Prevalence of Screening Colonoscopy among the First-Degree Relatives of Patients with Colorectal Cancer and Related Factors.Middle East journal of digestive diseases · 2025Article
- 25 year trends in cancer incidence and mortality among adults aged 35-69 years in the UK, 1993-2018: retrospective secondary analysis.BMJ (Clinical research ed.) · 2024Article
- Clinical significance of colonoscopy before laparoscopic bariatric/metabolic surgery in Japanese patients.Surgery today · 2024Article
- One-year review of real-time artificial intelligence (AI)-aided endoscopy performance.Surgical endoscopy · 2023Article
- Colorectal cancer mortality after spinal cord injury.The journal of spinal cord medicine · 2022Article
- Changing Metabolic Patterns along the Colorectal Adenoma-Carcinoma Sequence.Journal of clinical medicine · 2022Article
- Psychosocial Correlates of Experience and Intention to Receive Colorectal Cancer Screening: A Cross-Sectional Study Among East African Men in the U.S.The journal of primary prevention · 2021Article
- Vaccination with Polyclonal Antibody Stimulator (PAS) Prevents Pancreatic Carcinogenesis in the KRAS Mouse Model.Cancer prevention research (Philadelphia, Pa.) · 2021Article
- Artificial intelligence application in diagnostic gastrointestinal endoscopy - Deus ex machina?World journal of gastroenterology · 2021Review
- Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps.Cancer prevention research (Philadelphia, Pa.) · 2021Observational
- Impact of Endoscopists' Personality Traits on Adenoma and Polyp Detection Rates in Colonoscopy: A KASID Multicenter Study.Digestive diseases and sciences · 2020Article
- Patient randomized trial of a targeted navigation program to improve rates of follow-up colonoscopy in community health centers.Contemporary clinical trials · 2020Article
- Predicting colorectal polyp recurrence using time-to-event analysis of medical records.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020Article
- Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer.Journal of pancreatic cancer · 2020Article
- Colonoscopic screening is associated with reduced Colorectal Cancer incidence and mortality: a systematic review and meta-analysis.Journal of Cancer · 2020Article
- Additional value of linked color imaging in colonoscopy: a retrospective study.Endoscopy international open · 2019Article
- Clinical significance of colorectal polyp detection on colonoscopy insertion.United European gastroenterology journal · 2019Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are limited colonoscopy-based cohort data concerning the effectiveness of colonoscopy in reducing colorectal cancer deaths. The aim of this study was to clarify whether colonoscopy reduces colorectal cancer mortality.
methodsA cohort of 18,816 patients who underwent colonoscopy without a diagnosis of colorectal cancer between 2001 and 2010 at high colonoscopy procedure volume centers was selected. Patient characteristics and colonoscopy findings were assessed. The main endpoint was colorectal cancer death (all, right-sided, and left-sided cancers), and data were censored at the time of the final visit or the final colonoscopy. The standardized all colorectal, colon, and rectal cancer mortality rates were estimated with reference to those of the general Japanese population. Additional outcome was all- cause death and the standardized all-cause mortality rate was also estimated.
resultsThe total observed person-year mortality for colorectal cancer was 67,119. Of these, 4, 3, and 1 patients died from colorectal, colon, and rectal cancers, respectively; these values were significantly lower than the number of expected deaths in the general population, estimated to be 53.1, 34.0, and 19.1, respectively. The standardized mortalities for all colorectal, colon, and rectal cancers were 0.08 (95% confidence interval (CI), 0.02-0.17), 0.09 (95% CI, 0.02-0.22), and 0.05 (95% CI, 0.0002-0.21), respectively. There were 586 all-cause deaths (3.11%) during the observation period. The standardized all-cause mortality ratios were 0.22 (95% CI, 0.206-0.23).
conclusionsThe colorectal cancer mortality of patients who received colonoscopy without colorectal cancer diagnosis decreased significantly compared with that of individuals in the general population. These results were compatible even in patients with right-sided colon cancer.
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