Evidence map›Paper›PMID 28956522›Full record

ArticleEpidemiology and infection2017

Bovine leukaemia virus DNA in fresh milk and raw beef for human consumption.

N N Olaya-Galán, A P Corredor-Figueroa, T C Guzmán-Garzón, K S Ríos-Hernandez, S P Salas-Cárdenas, M A Patarroyo, M F Gutierrez

Open access · hybridAbstract read
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  6. Review
  7. The viral origins of breast cancer.Infectious agents and cancer · 2024
    Review
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  10. Article
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  13. Article
  14. Article
  15. Interrelated Oncogenic Viruses and Breast Cancer.Frontiers in molecular biosciences · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

N N Olaya-GalánPhD Programme in Biomedical and Biological Sciences,Universidad del Rosario,Bogotá,Colombia.ORCID 0000-0002-4282-4951
A P Corredor-FigueroaGrupo de Enfermedades Infecciosas, Laboratorio de Virología, Departamento de Microbiología,Pontificia Universidad Javeriana,Bogotá,Colombia.
T C Guzmán-GarzónGrupo de Enfermedades Infecciosas, Laboratorio de Virología, Departamento de Microbiología,Pontificia Universidad Javeriana,Bogotá,Colombia.
K S Ríos-HernandezGrupo de Enfermedades Infecciosas, Laboratorio de Virología, Departamento de Microbiología,Pontificia Universidad Javeriana,Bogotá,Colombia.
S P Salas-CárdenasGrupo de Enfermedades Infecciosas, Laboratorio de Virología, Departamento de Microbiología,Pontificia Universidad Javeriana,Bogotá,Colombia.
M A PatarroyoMolecular Biology and Immunology Department,Fundación Instituto de Inmunología de Colombia (FIDIC),Bogotá,Colombia.ORCID 0000-0002-4751-2500
M F GutierrezGrupo de Enfermedades Infecciosas, Laboratorio de Virología, Departamento de Microbiología,Pontificia Universidad Javeriana,Bogotá,Colombia.
Pontificia Universidad Javeriana · COFundación Instituto de Inmunología de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine leukaemia virus (BLV) is the causative agent of enzootic bovine leucosis, which has been reported worldwide. BLV has been found recently in human tissue and it could have a significant impact on human health. A possible hypothesis regarding viral entry to humans is through the consumption of infected foodstuffs. This study was aimed at detecting the presence of BLV DNA in raw beef and fresh milk for human consumption. Nested PCR directed at the BLV gag gene (272 bp) was used as a diagnostic test. PCR products were confirmed by Sanger sequencing. Forty-nine per cent of the samples proved positive for the presence of proviral DNA. This is the first study highlighting the presence of the BLV gag gene in meat products for human consumption and confirms the presence of the viral DNA in raw milk, as in previous reports. The presence of viral DNA in food products could suggest that viral particles may also be found. Further studies are needed to confirm the presence of infected viral particles, even though the present findings could represent a first approach to BLV transmission to humans through foodstuff consumption.

Indexed as

Leukemia Virus, BovineAnimalsCattleDNA, ViralEnzootic Bovine LeukosisHumansMeatMilkMultiplex Polymerase Chain ReactionPolymerase Chain ReactionSequence Analysis, DNADNA, ViralBovine leukaemia virusfoodborne infectionfresh milkraw meatzoonosis

Identifiers

PMID28956522
PMCPMC9148755
OpenAlexW2760196810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.