Evidence map›Paper›PMID 28956362›Full record

ReviewEndocrinology and metabolism (Seoul, Korea)2017

CTNNB1 Mutation in Aldosterone Producing Adenoma.

Jian Jhong Wang, Kang Yung Peng, Vin Cent Wu, Fen Yu Tseng, Kwan Dun Wu

Open access · diamondAbstract readReview
In one paragraph

Review in Endocrinology and metabolism (Seoul, Korea), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. CTNNB1 in neurodevelopmental disorders.Frontiers in psychiatry · 2023
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jian Jhong WangDivision of Nephrology, Department of Internal Medicine, Chi Mei Medical Center, Liouying, Tainan City, Taiwan.
Kang Yung PengTAIPAI (Taiwan Primary Aldosteronism investigator), Taipei, Taiwan.
Vin Cent WuTAIPAI (Taiwan Primary Aldosteronism investigator), Taipei, Taiwan.ORCID https://orcid.org/0000-0001-7935-0991
Fen Yu TsengTAIPAI (Taiwan Primary Aldosteronism investigator), Taipei, Taiwan.
Kwan Dun WuTAIPAI (Taiwan Primary Aldosteronism investigator), Taipei, Taiwan.
Aletheia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described and discussed in the literature. However, significant knowledge gaps still remain regarding the prevalence, clinical characteristics, pathophysiology, and outcomes in APA patients harboring CTNNB1 mutations. Aberrant activation of the Wnt/β-catenin signaling pathway will further modulate tumorigenesis. We also discuss the recent knowledge of CTNNB1 mutation in adrenal adenomas.

Indexed as

Aldosterone producing adenomasCBTNN1KCNJ5Primary aldosteronismTaiwan Primary Aldosteronism Investigator

Identifiers

PMID28956362
PMCPMC5620029
OpenAlexW2758615513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.