Evidence map›Paper›PMID 28956348›Full record

ReviewJournal of microbiology (Seoul, Korea)2017

Antibiofilm agents: A new perspective for antimicrobial strategy.

Xi-Hui Li, Joon-Hee Lee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 174 citations in OpenAlex.

  1. Intrapulmonary percussive ventilation improves lung function in cystic fibrosis patients chronically colonized with Pseudomonas aeruginosa: a pilot cross-over study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Trial
  2. Review
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  7. Current pharmaceutical biotechnology · 2026
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  8. Review
  9. Article
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  15. Review
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  17. Antibiofilm Strategies in Neonatal and Pediatric Infections.Antibiotics (Basel, Switzerland) · 2024
    Review
  18. Article
  19. Review
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xi-Hui LiDepartment of Pharmacy, College of Pharmacy, Pusan National University, Busan, 46241, Republic of Korea.
Joon-Hee LeeDepartment of Pharmacy, College of Pharmacy, Pusan National University, Busan, 46241, Republic of Korea. joonhee@pusan.ac.kr.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms are complex microbial architectures that attach to surfaces and encase microorganisms in a matrix composed of self-produced hydrated extracellular polymeric substances (EPSs). In biofilms, microorganisms become much more resistant to antimicrobial treatments, harsh environmental conditions, and host immunity. Biofilm formation by microbial pathogens greatly enhances survival in hosts and causes chronic infections that result in persistent inflammation and tissue damages. Currently, it is believed over 80% of chronic infectious diseases are mediated by biofilms, and it is known that conventional antibiotic medications are inadequate at eradicating these biofilm-mediated infections. This situation demands new strategies for biofilm-associated infections, and currently, researchers focus on the development of antibiofilm agents that are specific to biofilms, but are nontoxic, because it is believed that this prevents the development of drug resistance. Here, we review the most promising antibiofilm agents undergoing intensive research and development.

Indexed as

Anti-Infective AgentsAntimicrobial Cationic PeptidesBacterial InfectionsBiofilmsChelating AgentsDrug Resistance, MicrobialEnzymesFatty Acids, NonesterifiedHumansIndolesMicrobial Sensitivity TestsNitric Oxideortho-AminobenzoatesPolysaccharidesQuorum SensingSignal Transductionanthranilic acidAnti-Infective AgentsAntimicrobial Cationic PeptidesChelating AgentsEnzymesFatty Acids, NonesterifiedindoleIndolesNitric Oxideortho-AminobenzoatesPolysaccharidesSurface-Active Agentsantibiofilm agentbiofilm

Identifiers

PMID28956348
OpenAlexW2757050928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.