Evidence map›Paper›PMID 28956314›Full record

ReviewAdvances in experimental medicine and biology2018

New Insights in Cardiac Calcium Handling and Excitation-Contraction Coupling.

Jessica Gambardella, Bruno Trimarco, Guido Iaccarino, Gaetano Santulli

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
51.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 89 citations in OpenAlex.

  1. Trial
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  13. An In Vivo Model of Estrogen Supplementation Concerning the Expression of CaJournal of cardiovascular development and disease · 2024
    Article
  14. Article
  15. Article
  16. The role and mechanisms of microvascular damage in the ischemic myocardium.Cellular and molecular life sciences : CMLS · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Rapid Pacing Decreases L-type CaThe Journal of membrane biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jessica GambardellaDepartment of Advanced Biomedical Sciences, "Federico II" University, Naples, Italy.
Bruno TrimarcoDepartment of Advanced Biomedical Sciences, "Federico II" University, Naples, Italy.
Guido IaccarinoDepartment of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Fisciano, Italy.
Gaetano SantulliDepartment of Advanced Biomedical Sciences, "Federico II" University, Naples, Italy. gsantulli001@gmail.com.
Federico II University Hospital · ITAlbert Einstein College of Medicine · USUniversity of Salerno · IT

Funding

Targeting intracellular calcium leak as novel therapy for diabetesR00DK107895 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SANTULLI, GAETANO · 2018 to 2020
$741k
NIDDK NIH HHS R00 DK107895
6 · The paper itself

Abstract

Excitation-contraction (EC) coupling denotes the conversion of electric stimulus in mechanic output in contractile cells. Several studies have demonstrated that calcium (Ca

Indexed as

Excitation Contraction CouplingAnimalsBiomechanical PhenomenaCalciumHeart FailureHumansMyocardiumSystoleCalciumCalciumContractionHeart FailureMitochondriaRyRSerCa

Identifiers

PMID28956314
PMCPMC5889357
OpenAlexW2757102228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.