Evidence map›Paper›PMID 28956217›Full record

ArticleLasers in medical science2018

Chemoresistance to 5-FU inhibited by 635 nm LED irradiation in CD133+ KB cell line.

Donghwi Kim, Mineon Park, Hyunwoong Jang, Hoon Hyun, Wonbong Lim

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Donghwi KimDepartment of Orthopedic Surgery, Chosun University Hospital, Gwangju, 61453, South Korea.
Mineon ParkDepartment of Orthopedic Surgery, Chosun University Hospital, Gwangju, 61453, South Korea.
Hyunwoong JangDepartment of Orthopedic Surgery, Chosun University Hospital, Gwangju, 61453, South Korea.
Hoon HyunDepartment of Biomedical Sciences, Chonnam National University Medical School, Gwangju, 61469, South Korea.
Wonbong LimDepartment of Orthopedic Surgery, Chosun University Hospital, Gwangju, 61453, South Korea. wonbong@chosun.ac.kr.
Chosun University Hospital · KRChonnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consistent with cancer stem cell theory, a small fraction of cancer cells, described as cancer stem cells (CSCs), may promote tumor recurrence and anti-cancer drug resistance. Therefore, much effort has been devoted to the development of CSC targeted therapy to vanquish drug resistance. In this study, we have investigated the effect of multiple light-emitting diode (LED) irradiation treatments with conventional anti-cancer drugs on CSC-like oral cancer cells that acquired stemness by ectopic over expression of CD133. To evaluate combined LED irradiation anti-cancer drug effects, we investigated the chemosensitizing effect of 635 nm irradiation on 5-fluorouracil (5FU)-treated KB

Indexed as

LasersAC133 AntigenAnimalsAntineoplastic AgentsApoptosisBiomarkers, TumorCell Line, TumorCell ProliferationDrug Resistance, NeoplasmFluorouracilHumansMice, NudeNeoplasm Recurrence, LocalNeoplastic Stem CellsAC133 AntigenAntineoplastic AgentsBiomarkers, TumorFluorouracil5-FUCancer stem cellCD133Chemoresistance

Identifiers

PMID28956217
OpenAlexW2758745524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.