Evidence map›Paper›PMID 28956169›Full record

Trial reportInternational journal of biometeorology2018

Clinical improvement of patients with osteoarthritis using thermal mineral water at Szigetvár Spa-results of a randomised double-blind controlled study.

Adrienn Hanzel, Krisztina Horvát, Bálint Molics, Károly Berényi, Balázs Németh, Katalin Szendi, Csaba Varga

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International journal of biometeorology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04275206 naunknown statusnot on this mapstarted 2020, after this paper: background citation

The Anti-inflammatory Effects of Harkány Medicinal Water

TypeinterventionalSponsorUniversity of PecsRan2020 to 2023Enrolled350ConditionsRheumatoid Arthritis, PsoriasisArmsHarkány medicinal water, Tap water (placebo control)
NCT04290143 nacompletednot on this mapstarted 2020, after this paper: background citation

Introducing a New and Validated Placebo Development Method to Healing Water Based Rehabilitation Research

TypeinterventionalSponsorUniversity of PecsRan2020 to 2020Enrolled174ConditionsBalneologyArmsColored healing water, Placebo treatment (colored tap water)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Challenges of blinding in clinical balneology trials: a scoping review.BMC complementary medicine and therapies · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. To treat or not to treat? Misbeliefs in spa water disinfection.International journal of biometeorology · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adrienn HanzelDoctoral School, Faculty of Health Sciences, University of Pécs, Pécs, Hungary. adrienn.hanzel@gmail.com.
Krisztina HorvátHospital of Szigetvár, Szigetvár, Hungary.
Bálint MolicsFaculty of Health Sciences, University of Pécs, Pécs, Hungary.
Károly BerényiDepartment of Environmental Health, Institute of Public Health Medicine, University of Pécs, Pécs, Hungary.
Balázs NémethDepartment of Environmental Health, Institute of Public Health Medicine, University of Pécs, Pécs, Hungary.
Katalin SzendiDepartment of Environmental Health, Institute of Public Health Medicine, University of Pécs, Pécs, Hungary.
Csaba VargaDepartment of Environmental Health, Institute of Public Health Medicine, University of Pécs, Pécs, Hungary.
University of Pecs · HU

Funding

Medical School, University of Pécs KA-2016/34039New National Excellence Program of the Ministry of Human Capacities ÚNKP-17-3
6 · The paper itself

Abstract

Since 1966, Szigetvár in Hungary is well recognised as a thermal spa. Many patients suffering from rheumatic diseases are treated with its thermal mineral water. Our objective was to investigate the effects of a 3-week-long outpatient balneotherapy-based rehabilitation program on patients suffering from osteoarthritis of the hips and the knees. During the treatment period, patients received a 30-min underwater jet massage in a bath tub, five times a week. One patient group received jet massage in a bath tub containing mineral water; the other group received the same treatment in tap water. Primary outcomes were measured by range of movement of the involved joints and Western Ontario and McMaster University Osteoarthritis Index (WOMAC). Visual analogue scale (VAS) was applied to measure current severity of pain. Furthermore, quality of life was assessed using the Short Form 36 questionnaire (SF-36). Range of movement (ROM) score, Western Ontario and McMaster University Osteoarthritis Index and visual analogue scale were determined before the first treatment, after the last treatment and 3 months after the last treatment. SF-36 questionnaire was filled in before the first and after the last treatment. Fifty patients (17 male, 33 female mean age 66.7 ± 4.79 years) were enrolled. After randomisation, patients were divided into two groups: tap water n = 24 and mineral water n = 26. Treatment with the thermal mineral water of Szigetvár significantly improved ROM, WOMAC scores, and SF-36-scored quality of life of the patients. Our double-blind study provided evidence for the beneficial health effects of another Hungarian thermal mineral water masking the colour, odour and pH of the tap water and mineral water.

Indexed as

BalneologyAgedDouble-Blind MethodFemaleHumansHungaryMaleMiddle AgedMineral WatersOsteoarthritisTreatment OutcomeMineral WatersArthritisBalneotherapyThermal waterWOMAC

Identifiers

PMID28956169
OpenAlexW2756538100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.