Evidence map›Paper›PMID 28956011›Full record

ArticleBiochemistry and biophysics reports2017

CRISPR/Cas9-mediated simultaneous knockout of Dmrt1 and Dmrt3 does not recapitulate the 46,XY gonadal dysgenesis observed in 9p24.3 deletion patients.

Masafumi Inui, Moe Tamano, Tomoko Kato, Shuji Takada

Open access · goldAbstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Differentiation ofBiomolecules · 2025
    Article
  2. Article
  3. Article
  4. High Polymorphism in theAnimals : an open access journal from MDPI · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Masafumi InuiDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.
Moe TamanoDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.
Tomoko KatoDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.
Shuji TakadaDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.
National Center For Child Health and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DM domain transcription factors play important roles in sexual development in a wide variety of species from invertebrate to humans. Among seven mammalian family members of DM domain transcription factors, DMRT1 has been studied in mouse and human for its conserved role in male gonadal identity. Chromosomal deletion of 9p24.3, the region in which

Indexed as

CRISPR/Cas9Dmrt1Dmrt3Gonadal dysgenesisSexual developmentTestis

Identifiers

PMID28956011
PMCPMC5614593
OpenAlexW2569125401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.