Evidence map›Paper›PMID 28955942›Full record

ArticleBiochemistry and biophysics reports2016

Functional significance of active site residues in the enzymatic component of the

Abigail H Davies, Joanna McGlashan, Mareike G Posner, April K Roberts, Clifford C Shone, K Ravi Acharya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Importance of Therapeutically Targeting the Binary Toxin fromInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Abigail H DaviesDepartment of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Joanna McGlashanPublic Health England, Porton Down, Salisbury SP4 OJG, UK.
Mareike G PosnerDepartment of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.
April K RobertsPublic Health England, Porton Down, Salisbury SP4 OJG, UK.
Clifford C ShonePublic Health England, Porton Down, Salisbury SP4 OJG, UK.
K Ravi AcharyaDepartment of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Public Health England · GBUniversity of Bath · GB

Funding

Medical Research Council MR/K027123/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADP-ribosylationARTT, ADP-ribosyl turn-turnC2, C. botulinum toxin C2.CDTa, C. difficile toxin domain aCDTb, C. difficile toxin domain b residues 1-876CDTb′′, residues 209-876 of CDTb (no activation domain)CDTb′, residues 42-876 of CDTb (no signal peptide sequence)CDT, C. difficile binary toxinClostridium difficile binary toxinEnzymologyIa, C. perfringens Iota binary toxinMutagenesisrCDTa, recombinant wild-type C. difficile toxin domain aTcdA, C. difficile exotoxin ATcdB, C. difficile exotoxin B

Identifiers

PMID28955942
PMCPMC5613739
OpenAlexW2512834043

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.