ArticleBiochemistry and biophysics reports2016
Investigation of the antimicrobial activity of soy peptides by developing a high throughput drug screening assay.
Article in Biochemistry and biophysics reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Bioactive Plant Peptides: Physicochemical Features, Structure-Function Insights and Mechanism of Action.Molecules (Basel, Switzerland) · 2025Review
- Proteomic Characterization of a Lunasin-Enriched Soybean Extract Potentially Useful in the Treatment ofNutrients · 2024Article
- Exploring the nutritional and biological properties of green coffee extracts: A comparative study of aqueous and enzymatic extraction processes.Current research in food science · 2024Article
- Recent Trends in the Application of Oilseed-Derived Protein Hydrolysates as Functional Foods.Foods (Basel, Switzerland) · 2023Review
- Recent advances in exploring and exploiting soybean functional peptides-a review.Frontiers in nutrition · 2023Review
- Antimicrobial activities and mechanisms of extract and components of herbs in East Asia.RSC advances · 2022Review
- Phytochemicals: A Promising Weapon in the Arsenal against Antibiotic-Resistant Bacteria.Antibiotics (Basel, Switzerland) · 2021Review
- Valorization of Okara by Enzymatic Production of Anti-Fungal Compounds for Plant Protection.Molecules (Basel, Switzerland) · 2021Article
- Beneficial Effects of Soybean-Derived Bioactive Peptides.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial resistance is a great concern in the medical community, as well as food industry. Soy peptides were tested against bacterial biofilms for their antimicrobial activity. A high throughput drug screening assay was developed using microfluidic technology, RAMAN spectroscopy, and optical microscopy for rapid screening of antimicrobials and rapid identification of pathogens.
methodsSynthesized PGTAVFK and IKAFKEATKVDKVVVLWTA soy peptides were tested against
resultsThe PGTAVFK peptide did not significantly affect
conclusionsPGTAVFK and IKAFKEATKVDKVVVLWTA soy peptides showed antimicrobial activity against GENERAL SIGNIFICANCE: The results of this study show that the antimicrobial properties, biocompatibility, and biodegradability of soy peptides could possibly make them an alternative to the ineffective antimicrobials and antibiotics currently used in the food and medical fields. High throughput drug screening assays could help hasten pre-clinical trials in the medical field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.