Evidence map›Paper›PMID 28955825›Full record

ArticleBiochemistry and biophysics reports2016

Conditional deletion of CD98hc inhibits osteoclast development.

Hideki Tsumura, Morihiro Ito, Masamichi Takami, Miyuki Arai, Xiao-Kang Li, Toshio Hamatani, Arisa Igarashi, Shuji Takada, Kenji Miyado, Akihiro Umezawa and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. RNF219/Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hideki TsumuraDivision of Laboratory Animal Resources, National Research Institute for Child Health and Development, Tokyo, Japan.
Morihiro ItoDepartment of Microbiology, College of Life and Health Science, Chubu University, 1200 Matumoto-Chou, Kasugai-City, Aichi-Prefecture 487-8501, Japan.
Masamichi TakamiDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo, Japan.
Miyuki AraiDivision of Laboratory Animal Resources, National Research Institute for Child Health and Development, Tokyo, Japan.
Xiao-Kang LiDivision for Radiation Safety and Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Toshio HamataniDepartment of Obstetrics and Gynaecology, Keio University School of Medicine, Tokyo, Japan.
Arisa IgarashiDepartment of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Shuji TakadaDepartment of Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.
Kenji MiyadoDepartment of Reproductive Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Akihiro UmezawaDepartment of Reproductive Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Yasuhiko ItoDepartment of Microbiology, College of Life and Health Science, Chubu University, 1200 Matumoto-Chou, Kasugai-City, Aichi-Prefecture 487-8501, Japan.
National Center For Child Health and Development · JPChubu University · JPKeio University · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CD98 heavy chain (CD98hc) regulates virus-induced cell fusion and monocyte fusion, and is involved in amino acid transportation. Here, we examined the role that CD98hc plays in the formation of osteoclasts using CD98hc

Indexed as

Amino acid starvationAmino acid transportCD98 heavy chainIntegrin signalingOsteoclast formationRANKL

Identifiers

PMID28955825
PMCPMC5600448
OpenAlexW2189490874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.