Evidence map›Paper›PMID 28955658›Full record

ArticleFrontiers in oncology2017

CASTLE Thyroid Tumor: A Case Report and Literature Review.

Chris Lominska, Christopher Fleighton Estes, Prakash C Neupane, Y Shnayder, Mindi J TenNapel, Maura F O'Neil

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. The Molecular Landscape of CASTLE: A Rare Thymus-like Head and Neck Cancer.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Intrathyroid thymic carcinoma: report of a case].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Two cases of thyroid gland invasion by upper mediastinal carcinomaEndocrinology, diabetes & metabolism case reports · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chris LominskaRadiation Oncology, University of Kansas Medical Center, Kansas City, KS, United States.
Christopher Fleighton EstesRadiation Oncology, Mercy Clinic Radiation Oncology, Springfield, MO, United States.
Prakash C NeupaneMedical Oncology, University of Kansas Medical Center, Westwood, KS, United States.
Y ShnayderOtolaryngology, University of Kansas Medical Center, Kansas City, KS, United States.
Mindi J TenNapelRadiation Oncology, University of Kansas Medical Center, Kansas City, KS, United States.
Maura F O'NeilPathology, University of Kansas Medical Center, Kansas City, KS, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carcinoma showing thymus-like differentiation is a rare tumor of the thyroid gland, which is structurally similar to thymic tissue. Overall, it has a favorable prognosis. Radiotherapy has been shown to be an effective local treatment, but there have been reports of distant recurrence. It has been suggested that adding chemotherapy may decrease the risk of recurrence. Here, we present a case report of a patient with a large tumor and extrathyroidal extension. The patient was treated with surgery, radiotherapy, and cisplatin with acceptable toxicity. The patient is free of locally recurrent or distant disease at 3 years.

Indexed as

case reportCASTLEradiation therapythyroid carcinomathyroid tumor

Identifiers

PMID28955658
PMCPMC5602351

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.