Evidence map›Paper›PMID 28955435›Full record

SynthesisMalawi medical journal : the journal of Medical Association of Malawi2017

Exposure to biomass smoke as a risk factor for oesophageal and gastric cancer in low-income populations: A systematic review.

Violet Kayamba, Douglas C Heimburger, Douglas R Morgan, Masharip Atadzhanov, Paul Kelly

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Malawi medical journal : the journal of Medical Association of Malawi, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Air Quality and Cancer Prevalence Trends across the Sub-Saharan African Regions during 2005-2020.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Sugary Liquids in the Baby Bottle: Risk for Child Undernutrition and Severe Tooth Decay in Rural El Salvador.International journal of environmental research and public health · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Violet KayambaTropical Gastroenterology & Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Douglas C HeimburgerVanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee, USA.
Douglas R MorganVanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee, USA.
Masharip AtadzhanovDepartment of Internal Medicine, University of Zambia School of Medicine, Lusaka, Zambia.
Paul KellyTropical Gastroenterology & Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Queen Mary University of London · GBTropical Gastroenterology & Nutrition group · ZMUniversity of Zambia · ZMVanderbilt Health · USVanderbilt University · US

Funding

Project 3 - Molecular Signatures of Gastric Carcinogenesis in the Host Response to H. pyloriP01CA028842 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, KEITH T. · 1985 to 2019
$15.8M
NCI NIH HHS P01 CA028842
6 · The paper itself

Abstract

backgroundUpper gastrointestinal cancers contribute significantly to cancer-related morbidity and mortality in sub-Saharan Africa, but they continue to receive limited attention. The high incidence in young adults remains unexplained, and the risk factors have not been fully described.

methodsA literature search was conducted using the electronic database PubMed. Beginning from January 1980 to February 2016, all articles evaluating biomass smoke exposure with oesophageal and gastric cancer were reviewed.

resultsOver 70% of the African population relies on biomass fuel, meaning most Africans are exposed to biomass smoke throughout their lives. Cigarette smoke is an established risk factor for upper gastrointestinal cancers, and some of its carcinogenic constituents are also present in biomass smoke. We found eight case-control studies reporting associations between exposure to biomass smoke and oesophageal cancer, and two linking biomass smoke to gastric cancer. All of these papers reported significant positive associations between exposure and cancer risk. Further research is needed in order to fully define the constituents of biomass smoke, which could each have varying specific and synergistic or independent contributions to the development of upper gastrointestinal cancers.

conclusionsExposure to biomass smoke is an environmental factor influencing the development of upper gastrointestinal cancers, especially in low-resource settings.

Indexed as

BiomassPovertyAir Pollution, IndoorEsophageal NeoplasmsHumansRisk FactorsSmokeStomach NeoplasmsSmoke

Identifiers

PMID28955435
PMCPMC5610298
OpenAlexW2745536087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.