ArticleMalawi medical journal : the journal of Medical Association of Malawi2017
Human papillomavirus in head and neck squamous cell carcinoma: A descriptive study of histologically confirmed cases at Kamuzu Central Hospital in Lilongwe, Malawi.
Article in Malawi medical journal : the journal of Medical Association of Malawi, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Human Papillomavirus-Associated Head and Neck Malignancies in Sub-Saharan Africa: A Systematic Review.JCO global oncology · 2023Pooled it
- PREVALENCE, CHARACTERISTICS AND TREATMENT OUTCOMES OF HPV POSITIVE OROPHARYNGEAL CARCINOMA IN AFRICA: A SYSTEMATIC REVIEW AND META-ANALYaSIS.Annals of Ibadan postgraduate medicine · 2026Article
- Update on pathology laboratory development and research in advancing regional cancer care in Malawi.Frontiers in medicine · 2024Article
- Awareness of Cancer Risk Factors and Its Signs and Symptoms in Northern Tanzania: a Cross-Sectional Survey in the General Population and in People Living with HIV.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020Article
- A descriptive study of human papilloma virus in upper aero-digestive squamous cell carcinoma at Uganda cancer institute assessed by P16 immunohistochemistry.Cancers of the head & neck · 2020Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundHead and neck squamous cell carcinoma (HNSCC) is common in sub-Saharan Africa, but the aetiologic contribution of human papillomavirus (HPV) is not well established.
methodsWe assessed HNSCC cases for HPV using p16 immunohistochemistry (IHC) in Malawi. Associations between p16 IHC and tumour site, behavioural risk factors, demographic characteristics, and HIV status were examined.
resultsFrom 2010 to 2014, 77 HNSCC cases were identified. Mean age was 52 years, 50 cases (65%) were male, and 48 (62%) were in the oropharynx (OP) or oral cavity (OC). HIV status was known for 35 patients (45%), with 5 (14%) HIV-infected. Substance use was known for 40 patients (52%), with 38% reporting any tobacco and 31% any alcohol. Forty-two cases (55%) had adequate tissue for p16 IHC, of which seven (17%) were positive, including 22% of OP/OC tumours.
conclusionsDespite high cervical cancer burden, HPV-associated HNSCC is not very common in Malawi.
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