Evidence map›Paper›PMID 28955255›Full record

ArticleFrontiers in psychiatry2017

Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder.

Peter Sörös, Katharina Bachmann, Alexandra P Lam, Manuela Kanat, Eliza Hoxhaj, Swantje Matthies, Bernd Feige, Helge H O Müller, Christiane Thiel, Alexandra Philipsen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Peter SörösSchool of Medicine and Health Sciences, Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, University of Oldenburg, Oldenburg, Germany.
Katharina BachmannSchool of Medicine and Health Sciences, Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, University of Oldenburg, Oldenburg, Germany.
Alexandra P LamSchool of Medicine and Health Sciences, Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, University of Oldenburg, Oldenburg, Germany.
Manuela KanatDepartment of Psychology, Laboratory for Biological Psychology, University of Freiburg, Freiburg, Germany.
Eliza HoxhajFaculty of Medicine, Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Freiburg, Germany.
Swantje MatthiesFaculty of Medicine, Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Freiburg, Germany.
Bernd FeigeFaculty of Medicine, Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Freiburg, Germany.
Helge H O MüllerSchool of Medicine and Health Sciences, Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, University of Oldenburg, Oldenburg, Germany.
Christiane ThielResearch Center Neurosensory Science, University of Oldenburg, Oldenburg, Germany.
Alexandra PhilipsenSchool of Medicine and Health Sciences, Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, University of Oldenburg, Oldenburg, Germany.
Carl von Ossietzky Universität Oldenburg · DEUniversity Medical Center Freiburg · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAttention-deficit/hyperactivity disorder (ADHD) in adulthood is a serious and frequent psychiatric disorder with the core symptoms inattention, impulsivity, and hyperactivity. The principal aim of this study was to investigate associations between brain morphology, i.e., cortical thickness and volumes of subcortical gray matter, and individual symptom severity in adult ADHD.

methodsSurface-based brain morphometry was performed in 35 women and 29 men with ADHD using FreeSurfer. Linear regressions were calculated between cortical thickness and the volumes of subcortical gray matter and the inattention, hyperactivity, and impulsivity subscales of the Conners Adult ADHD Rating Scales (CAARS). Two separate analyses were performed. For the first analysis, age was included as additional regressor. For the second analysis, both age and severity of depression were included as additional regressors. Study participants were recruited between June 2012 and January 2014.

resultsLinear regression identified an area in the left occipital cortex of men, covering parts of the middle occipital sulcus and gyrus, in which the score on the CAARS inattention subscale predicted increased mean cortical thickness [

conclusionIncreased cortical thickness in the left occipital cortex may represent a mechanism to compensate for dysfunctional attentional networks in male adult ADHD patients.

Indexed as

attentionattention-deficit/hyperactivity disordercortical thicknessFreeSurfergray mattermorphometryoccipital cortex

Identifiers

PMID28955255
PMCPMC5601484
OpenAlexW2754875913

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.