Evidence map›Paper›PMID 28955218›Full record

ArticleFrontiers in aging neuroscience2017

Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Show Different but Partially Overlapping Profile Compared to Vascular Dementia.

Franc Llorens, Matthias Schmitz, Tobias Knipper, Christian Schmidt, Peter Lange, Andre Fischer, Peter Hermann, Inga Zerr

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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  14. Methylation of theNeuropsychiatric disease and treatment · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Franc LlorensDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Matthias SchmitzDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Tobias KnipperDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Christian SchmidtDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Peter LangeDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Andre FischerGerman Center for Neurodegenerative Diseases-DZNE Site GöttingenBonn, Germany.
Peter HermannDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Inga ZerrDepartment of Neurology, Universitätsmedizin GöttingenGöttingen, Germany.
Universitätsmedizin Göttingen · DEGerman Center for Neurodegenerative Diseases · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular factors increase the risks of developing Alzheimer's disease (AD) and they contribute to AD pathology. Since amyloid beta (Aβ) deposits can be observed in both diseases, there is an overlap which impedes a clear discrimination and difficult clinical diagnosis. In the present study, we compared cerebrospinal fluid (CSF) profiles of neurodegenerative and inflammatory biomarkers in a patient cohort of controls (

Indexed as

Alzheimer's diseaseamyloid betabiomarkerscerebrospinal fluidneurodegenerationtauvascular dementiavascular encephalopathy

Identifiers

PMID28955218
PMCPMC5601075
OpenAlexW2754357918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.