Evidence map›Paper›PMID 28954921›Full record

ArticleStroke2017

Synergism of Short-Term Air Pollution Exposures and Neighborhood Disadvantage on Initial Stroke Severity.

Jeffrey J Wing, Brisa N Sánchez, Sara D Adar, William J Meurer, Lewis B Morgenstern, Melinda A Smith, Lynda D Lisabeth

Abstract read
In one paragraph

Article in Stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Housing and Stroke Outcomes: Why Aging in Place Needs to Be Equitable.International journal of environmental research and public health · 2026
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  15. Article
  16. Air Pollution and Ischaemic Stroke.Annals of Indian Academy of Neurology · 2022
    Article
  17. Article
  18. Article
  19. Misuse of Pollution Reference Standards: No Safe Level of Air Pollution.American journal of respiratory and critical care medicine · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey J WingFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan. wingje@gvsu.edu.
Brisa N SánchezFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan.
Sara D AdarFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan.
William J MeurerFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan.
Lewis B MorgensternFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan.
Melinda A SmithFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan.
Lynda D LisabethFrom the Department of Epidemiology, School of Public Health (J.J.W., S.D.A., L.B.M., L.D.L.), Department of Biostatistics, School of Public Health (B.N.S.), Department of Neurology, Stroke Program (W.J.M., L.B.M., M.A.S., L.D.L.), and Department of Emergency Medicine (W.J.M.), University of Michigan.

Funding

STROKE SURVEILLANCE IN A BIETHNIC COMMUNITYR01NS038916 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LISABETH, LYNDA D, MORGENSTERN, LEWIS B · 1999 to 2023
$20.9M
NINDS NIH HHS R01 NS038916
6 · The paper itself

Abstract

background and purposeLittle is known about the relation between environment and stroke severity. We investigated associations between environmental exposures, including neighborhood socioeconomic disadvantage and short-term exposure to airborne particulate matter <2.5 μm and ozone, and their interactions with initial stroke severity.

methodsFirst-ever ischemic stroke cases were identified from the Brain Attack Surveillance in Corpus Christi project (2000-2012). Associations between pollutants, disadvantage, and National Institutes of Health Stroke Scale were modeled using linear and logistic regression with adjustment for demographics and risk factors. Pollutants and disadvantage were modeled individually, jointly, and with interactions.

resultsHigher disadvantage scores and previous-day ozone concentrations were associated with higher odds of severe stroke. Higher levels of particulate matter <2.5 μm were associated with higher odds of severe stroke among those in higher disadvantage areas (odds ratio, 1.24; 95% confidence interval, 1.00-1.55) but not in lower disadvantage areas (odds ratio, 0.82; 95% confidence interval, 0.56-1.22;

conclusionsAir pollution exposures and neighborhood socioeconomic status may be important in understanding stroke severity. Future work should consider the multiple levels of influence on this important stroke outcome.

Indexed as

Severity of Illness IndexAgedAged, 80 and overAir PollutionBrain IschemiaFemaleHumansMaleMichiganMiddle AgedOzoneRetrospective StudiesSocioeconomic FactorsStrokeOzoneischemic strokeneighborhood disadvantageozoneparticulate matterstroke severity

Identifiers

PMID28954921
PMCPMC5679432

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.