ArticleProceedings. Biological sciences2017
Offspring genes indirectly influence sibling and maternal behavioural strategies over resource share.
Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- New Insights on Gene by Environmental Effects of Drugs of Abuse in Animal Models Using GeneNetwork.Genes · 2022Article
- Indirect Genetic Effects: A Cross-disciplinary Perspective on Empirical Studies.The Journal of heredity · 2022Article
- Dissecting indirect genetic effects from peers in laboratory mice.Genome biology · 2021Article
- Behavior Testing in Rodents: Highlighting Potential Confounds Affecting Variability and Reproducibility.Brain sciences · 2021Review
- The role of interindividual licking received and dopamine genotype on later-life licking provisioning in female rat offspring.Brain and behavior · 2021Article
- Article
- No evidence for sibling or parent-offspring coadaptation in a wild population of blue tits, despite high power.Evolution; international journal of organic evolution · 2019Article
- Post-genomic behavioral genetics: From revolution to routine.Genes, brain, and behavior · 2018Review
- Born to Cry: A Genetic Dissection of Infant Vocalization.Frontiers in behavioral neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Family members show behavioural strategies predicted to maximize individual fitness. These behaviours depend directly on genes expressed in focal individuals but also indirectly on genes expressed in other family members. However, how sibling and parental behavioural strategies are modified by genes expressed in family members, and to what degree, remains unclear. To answer this question, we have used a split litter design in an experimental population of genetically variable mouse families, and identified loci that indirectly affected sibling and maternal behaviour simultaneously. These loci map to genomic regions that also show a direct effect on offspring behaviour. Directly and indirectly affected traits were significantly correlated at the phenotypic level, illustrating how indirect effects are caused. Genetic variants in offspring that influence solicitation also impacted their siblings' and maternal behaviour. However, in contrast to predictions from sibling competition, unrelated litter mates benefited from increased solicitation. Overall, such indirect genetic effects explained a large proportion of variation seen in behaviours, with candidate genes involved in metabolism to neuronal development. These results reveal that we need to view behavioural strategies as the result of conjoint selection on genetic variation in all interacting family members.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.