Evidence map›Paper›PMID 28954858›Full record

ArticleMolecular biology of the cell2017

Modeling neutrophil migration in dynamic chemoattractant gradients: assessing the role of exosomes during signal relay.

Alex C Szatmary, Ralph Nossal, Carole A Parent, Ritankar Majumdar

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  15. DAMPs and NETs in Sepsis.Frontiers in immunology · 2019
    Review
  16. Collective gradient sensing and chemotaxis: modeling and recent developments.Journal of physics. Condensed matter : an Institute of Physics journal · 2018
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alex C SzatmaryDivision of Basic and Translational Biophysics, National Institute of Child Health and Human Development, Rockville, MD 20847.
Ralph NossalDivision of Basic and Translational Biophysics, National Institute of Child Health and Human Development, Rockville, MD 20847.
Carole A ParentLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 ritankar@umich.edu parentc@umich.edu.
Ritankar MajumdarLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 ritankar@umich.edu parentc@umich.edu.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migrating cells often exhibit signal relay, a process in which cells migrating in response to a chemotactic gradient release a secondary chemoattractant to enhance directional migration. In neutrophils, signal relay toward the primary chemoattractant N--formylmethionyl-leucyl-phenylalanine (fMLP) is mediated by leukotriene B

Indexed as

Cell MovementChemotactic FactorsChemotaxisChemotaxis, LeukocyteExosomesHumansInterleukin-8Leukotriene B4Models, TheoreticalNeutrophilsN-Formylmethionine Leucyl-PhenylalanineSignal TransductionChemotactic FactorsInterleukin-8Leukotriene B4N-Formylmethionine Leucyl-Phenylalanine

Identifiers

PMID28954858
PMCPMC5687044
OpenAlexW2760439620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.