Evidence map›Paper›PMID 28954791›Full record

Trial reportBMJ open2017

Mii-vitaliSe: a pilot randomised controlled trial of a home gaming system (Nintendo Wii) to increase activity levels, vitality and well-being in people with multiple sclerosis.

Sarah Thomas, Louise Fazakarley, Peter W Thomas, Sarah Collyer, Sarah Brenton, Steve Perring, Rebecca Scott, Fern Thomas, Charlotte Thomas, Kelly Jones and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07713342 (The Efficacy of Virtual Reality Training on Medial Epicondyle Apophysitis in Adolescent Athletes), which is not on this map. Cited by 36 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07713342 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Efficacy of Virtual Reality Training on Medial Epicondyle Apophysitis in Adolescent Athletes

TypeinterventionalSponsorSouth Valley UniversityRan2026 to 2026Enrolled60ConditionsAdolescent Athelets, Medial Epicondyle ApophysitisArmsThe Control Group, The Study Group
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 16 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Virtual reality for multiple sclerosis rehabilitation.The Cochrane database of systematic reviews · 2025
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  9. Effect of home-based virtual reality training and telerehabilitation on balance in individuals with Parkinson disease, multiple sclerosis, and stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
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  17. Cost-effectiveness analysis of the MYO ArmbandJournal of neuroengineering and rehabilitation · 2025
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarah ThomasBournemouth University, Faculty of Health and Social Sciences, Bournemouth, Dorset, UK.ORCID http://orcid.org/0000-0002-9501-9091
Louise FazakarleyBournemouth University, Faculty of Health and Social Sciences, Bournemouth, Dorset, UK.
Peter W ThomasBournemouth University, Faculty of Health and Social Sciences, Bournemouth, Dorset, UK.
Sarah CollyerPoole Hospital NHS Foundation Trust, Dorset Multiple Sclerosis Service, Poole, Dorset, UK.
Sarah BrentonPoole Hospital NHS Foundation Trust, Dorset Multiple Sclerosis Service, Poole, Dorset, UK.
Steve PerringPoole Hospital NHS Foundation Trust, Medical Physics, Poole, Dorset, UK.
Rebecca ScottNational Star College, Cheltenham, Gloucestershire, UK.
Fern ThomasBournemouth University, Faculty of Health and Social Sciences, Bournemouth, Dorset, UK.
Charlotte ThomasBournemouth University, Faculty of Health and Social Sciences, Bournemouth, Dorset, UK.
Kelly JonesService user, Bournemouth, UK.
Jo HicksonService user, Bournemouth, UK.
Charles HillierPoole Hospital NHS Foundation Trust, Dorset Multiple Sclerosis Service, Poole, Dorset, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWhile the health and well-being benefits of physical activity are recognised, people with multiple sclerosis (MS) often face greater barriers than the general population. The Nintendo Wii potentially offers a fun, convenient way of overcoming some of these. The aim was to test the feasibility of conducting a definitive trial of the effectiveness and cost-effectiveness of Mii-vitaliSe; a home-based, physiotherapist-supported Nintendo Wii intervention.

designA single-centre wait-list randomised controlled study.

settingMS service in secondary care.

participantsAmbulatory, relatively inactive people with clinically confirmed MS.

interventionThirty participants were randomised to receive Mii-vitaliSe either immediately (for 12 months) or after a 6-month wait (for 6 months). Mii-vitaliSe consisted of two supervised Nintendo Wii familiarisation sessions in the hospital followed by home use (Wii Sports, Sports Resort and Fit Plus software) with physiotherapist support and personalised resources. OUTCOMES: Included self-reported physical activity levels, quality of life, mood, self-efficacy, fatigue and assessments of balance, gait, mobility and hand dexterity at baseline, 6 and 12 months. Interviews (n=25) explored participants' experiences and, at study end, the two Mii-vitaliSe facilitators' experiences of intervention delivery (main qualitative findings reported separately).

resultsMean (SD) age was 49.3 (8.7) years, 90% female, with 47% diagnosed with MS <6 years ago and 60% new to active gaming. The recruitment rate was 31% (95% CI 20% to 44%). Outcome data were available for 29 (97%) at 6 months and 28 (93%) at 12 months. No serious adverse events were reported during the study. Qualitative data indicated that Mii-vitaliSe was well-received. Mean Wii use across both groups over the initial 6-month intervention period was twice a week for 27 min/day. Mean cost of delivering Mii-vitaliSe was £684 per person. DISCUSSION: Mii-vitaliSe appears acceptable and a future trial feasible and warranted. These findings will inform its design.

trial registrationISRCTN49286846.

Indexed as

ExerciseQuality of LifeVideo GamesExercise TherapyFatigueFeasibility StudiesHumansMiddle AgedMultiple SclerosisPilot ProjectsQualitative ResearchSecondary Health CareSelf ReportActive GamingBehaviour changeExerciseFeasibilityMultiple SclerosisPhysical ActivityVirtual Reality

Identifiers

PMID28954791
PMCPMC5623500

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.