Evidence map›Paper›PMID 28954688›Full record

ArticleMicrobiology (Reading, England)2017

A manganese photosensitive tricarbonyl molecule [Mn(CO)3(tpa-κ

Namrata Rana, Helen E Jesse, Mariana Tinajero-Trejo, Jonathan A Butler, John D Tarlit, Milena L von Und Zur Muhlen, Christoph Nagel, Ulrich Schatzschneider, Robert K Poole

Open access · hybridAbstract read
In one paragraph

Article in Microbiology (Reading, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Namrata RanaDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
Helen E JesseDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
Mariana Tinajero-TrejoDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
Jonathan A ButlerDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
John D TarlitDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
Milena L von Und Zur MuhlenDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
Christoph NagelInstitut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Ulrich SchatzschneiderInstitut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Robert K PooleDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, UK.
University of Sheffield · GBUniversity of Würzburg · DEManchester Metropolitan University · GB

Funding

Biotechnology and Biological Sciences Research Council BB/H016805/1
6 · The paper itself

Abstract

Carbon monoxide-releasing molecules (CORMs) are a promising class of new antimicrobials, with multiple modes of action that are distinct from those of standard antibiotics. The relentless increase in antimicrobial resistance, exacerbated by a lack of new antibiotics, necessitates a better understanding of how such novel agents act and might be used synergistically with established antibiotics. This work aimed to understand the mechanism(s) underlying synergy between a manganese-based photoactivated carbon monoxide-releasing molecule (PhotoCORM), [Mn(CO)3(tpa-κ

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsAntiportersBacterial ProteinsCarbon MonoxideEscherichia coliIronManganesePhotosensitizing AgentsAnti-Bacterial AgentsAntiportersBacterial ProteinsCarbon MonoxideIronManganesePhotosensitizing AgentstetA protein, Bacteriaantibiotic resistanceantimicrobial agentsbacterial pathogenesiscarbon monoxideEscherichia colimanganese complexphotosensitive tricarbonyl complex

Identifiers

PMID28954688
PMCPMC5845575
OpenAlexW2760455171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.