Evidence map›Paper›PMID 28954106›Full record

ArticleAnais brasileiros de dermatologia

Trichotillomania: a good response to treatment with N-acetylcysteine.

Livia Ariane Lopes Barroso, Flavia Sternberg, Maria Natalia Inacio de Fraia E Souza, Gisele Jacobino de Barros Nunes

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04209803 (Efficacy and Tolerability of N-Acetyl- Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04209803 phase4completednot on this map

Efficacy and Tolerability of N-Acetyl- Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

TypeinterventionalSponsorKafrelsheikh UniversityRan2018 to 2020Enrolled100ConditionsAndrogenetic AlopeciaArmsMinoxidil 5% topically and oral NAC 600 mg
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Body Focused Repetitive Behavior Disorders: Behavioral Models and Neurobiological Mechanisms.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2023
    Review
  2. Eyebrow and Eyelash Alopecia: A Clinical Review.American journal of clinical dermatology · 2023
    Review
  3. The Potential ofInternational journal of environmental research and public health · 2022
    Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Livia Ariane Lopes BarrosoTrichology Outpatient Clinic, Department of Cosmetology, Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil.
Flavia SternbergTrichology Outpatient Clinic, Department of Cosmetology, Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil.
Maria Natalia Inacio de Fraia E SouzaTrichology Outpatient Clinic, Department of Cosmetology, Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil.
Gisele Jacobino de Barros NunesTrichology Outpatient Clinic, Department of Cosmetology, Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil.
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichotillomania is considered a behavioral disorder and is characterized by the recurring habit of pulling one's hair, resulting in secondary alopecia. It affects 1% of the adult population, and 2 to 4.4% of psychiatric patients meet the diagnostic criteria. It can occur at any age and is more prevalent in adolescents and females. Its occurrence in childhood is not uncommon and tends to have a more favorable clinical course. The scalp, eyebrows and eyelashes are the most commonly affected sites. Glutamate modulating agents, such as N-acetylcysteine, have been shown to be a promising treatment. N-acetylcysteine acts by reducing oxidative stress and normalizing glutaminergic transmission. In this paper, we report a case of trichotillomania with an excellent response to N-acetylcysteine.

Indexed as

AcetylcysteineAlopeciaAntioxidantsChildDiagnosis, DifferentialHumansMaleTrichotillomaniaAcetylcysteineAntioxidants

Identifiers

PMID28954106
PMCPMC5595604
OpenAlexW2754295697

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.