Observational studyClinics (Sao Paulo, Brazil)2017
Independent early predictors of mortality in polytrauma patients: a prospective, observational, longitudinal study.
Observational study in Clinics (Sao Paulo, Brazil), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01669577 (Independent Predictors of Mortality in Polytrauma Patients), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Independent Predictors of Mortality in Polytrauma Patients: a Prospective, Observational, Longitudinal Study
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The potential of point-of-care diagnostics to optimise prehospital trauma triage: a systematic review of literature.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Systematic review of oxygenation and clinical outcomes to inform oxygen targets in critically ill trauma patients.The journal of trauma and acute care surgery · 2019Pooled it
- 25-Year experience with adult polytraumatized patients in a European level 1 trauma center: polytrauma between 1995 and 2019. What has changed? A retrospective cohort study.Archives of orthopaedic and trauma surgery · 2023Trial
- Influence of the Region of Injury on Risk of Mortality in Severely Injured Patients Stratified by Age: An Analysis of 98,481 Patients from the TraumaRegister DGUJournal of clinical medicine · 2026Article
- Evaluation of a portable, lightweight modular system to deliver high inspired oxygen to trauma casualties without the use of pressurised cylinders.BMJ military health · 2026Article
- Incidence and predictors of early mortality among trauma patients visiting emergency departments of referral hospitals in west Amhara region, Ethiopia.Scientific reports · 2026Observational
- Effect of different factors on predicting patient mortality beyond the NACA classification: a multivariate analysis of more than 2,000 polytrauma patients.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Article
- On-scene predictors of injury severity, deterioration, and death following road injury: a systematic scoping review of information available to responders and its use in triage tools.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Article
- Prehospital care utilization and associated factors among trauma patients during armed conflict: A mixed-methods study in west Amhara, Ethiopia referral hospitals.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025Article
- Polytrauma Cases in the Emergency Department of a Community Hospital in Croatia.Journal of personalized medicine · 2025Article
- Clinical characteristics and mortality risk factors in polytrauma patients with pelvic fractures: a retrospective study based on an integrated multidisciplinary treatment approach.International journal of emergency medicine · 2025Article
- Long-Term Functional Recovery after Severe Traumatic Brain Injury with Type II Diffuse Injury.Neurotrauma reports · 2025Article
- Admission Blood Glucose Level with a Cutoff Value of 15 mmol/L Is a Reliable Predictor of Mortality in Polytraumatized Patients-a Prospective, Observational, Longitudinal Study From a North African Level One Trauma Center.Orthopedic research and reviews · 2025Article
- The NACA score predicts mortality in polytrauma patients before hospital admission: a registry-based study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Survival status and its predictors among adult victims of road traffic accident admitted to public hospitals of Bahir Bar City, Amhara regional state, Northwest, Ethiopia, 2023: multi center retrospective follow-up study.BMC emergency medicine · 2024Article
- Predicting the complexity and mortality of polytrauma patients with machine learning models.Scientific reports · 2024Article
- Independent predictors of mortality for critically ill patients with polytrauma: A single center, retrospective study.Heliyon · 2024Article
- Mortality Risk Factors of Severely Injured Polytrauma Patients (Prehospital Mortality Prediction Score).Journal of clinical medicine · 2023Article
- The sequence of the treatment of combined fractures of the pelvis, spine, and extremities in polytraumatized patients.EFORT open reviews · 2023Review
- Predicting mortality in severe polytrauma with limited resources.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectives: Trauma is an important public health issue and associated with substantial socioeconomic impacts and major adverse clinical outcomes. No single study has previously investigated the predictors of mortality across all stages of care (pre-hospital, emergency room, surgical center and intensive care unit) in a general trauma population. This study was designed to identify early predictors of mortality in severely injured polytrauma patients across all stages of care to provide a better understanding of the physiologic changes and mechanisms by which to improve care in this population.
methods: A longitudinal, prospective, observational study was conducted between 2010 and 2013 in São Paulo, Brazil. Patients submitted to high-energy trauma were included. Exclusion criteria were as follows: injury severity score <16, <18 years old or insufficient data. Clinical and laboratory data were collected at four time points: pre-hospital, emergency room, and 3 and 24 hours after hospital admission. The primary outcome assessed was mortality within 30 days. Data were analyzed using tests of association as appropriate, nonparametric analysis of variance and generalized estimating equation analysis (p<0.05). ClinicalTrials.gov: NCT01669577.
results: Two hundred patients were included. Independent early predictors of mortality were as follows: arterial hemoglobin oxygen saturation (p<0.001), diastolic blood pressure (p<0.001), lactate level (p<0.001), Glasgow Coma Scale score (p<0.001), infused crystalloid volume (p<0.015) and presence of traumatic brain injury (p<0.001).
conclusion: Our results suggest that arterial hemoglobin oxygen saturation, diastolic blood pressure, lactate level, Glasgow Coma Scale, infused crystalloid volume and presence of traumatic brain injury are independent early mortality predictors.
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