Evidence map›Paper›PMID 28953976›Full record

ArticlePloS one2017

Serological evidence of arenavirus circulation among fruit bats in Trinidad.

Ashley Malmlov, Janine Seetahal, Christine Carrington, Vernie Ramkisson, Jerome Foster, Kerri L Miazgowicz, Sandra Quackenbush, Joel Rovnak, Oscar Negrete, Vincent Munster and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  8. Review
  9. Review
  10. Article
  11. Article
  12. Hematologic Values of Jamaican Fruit Bats (Journal of the American Association for Laboratory Animal Science : JAALAS · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ashley MalmlovArthropod-borne and Infectious Disease Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Janine SeetahalDepartment of Preclinical Sciences, Faculty of Medical Science, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago.
Christine CarringtonDepartment of Preclinical Sciences, Faculty of Medical Science, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago.
Vernie RamkissonDepartment of Preclinical Sciences, Faculty of Medical Science, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago.
Jerome FosterDepartment of Preclinical Sciences, Faculty of Medical Science, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago.
Kerri L MiazgowiczSandia National Laboratories, Biotechnology and Bioengineering, Livermore, California, United States of America.
Sandra QuackenbushDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Joel RovnakDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Oscar NegreteSandia National Laboratories, Biotechnology and Bioengineering, Livermore, California, United States of America.
Vincent MunsterVirus Ecology Unit, Laboratory of Virology, Rocky Mountain Laboratories, NIAID/NIH, Hamilton, Montana, United States of America.
Tony SchountzArthropod-borne and Infectious Disease Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.ORCID http://orcid.org/0000-0002-1292-7650
Colorado State University · USUniversity of the West Indies · TTSandia National Laboratories California · US

Funding

Virus Ecology UnitZIAAI001179 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MUNSTER, VINCENT · 2013 to 2025
$24.3M
International Research in CongoZIAAI001190 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MUNSTER, VINCENT · 2014 to 2025
$3.4M
Experimental Tacaribe Virus Infection of Jamaican Fruit BatsR15AI089419 · NIAID · UNIVERSITY OF NORTHERN COLORADO · PI SCHOUNTZ, WILLIAM A · 2010 to 2010
$403k
U.S. Based Collaboration in Emerging Viral and Prion Diseases-26625489N01AI025489 · NIAID · University of Texas Medical Branch · 2004 to 2004
–
NIAID NIH HHS N01 AI025489NIAID NIH HHS R15 AI089419
6 · The paper itself

Abstract

Tacaribe virus (TCRV) was isolated in the 1950s from artibeus bats captured on the island of Trinidad. The initial characterization of TCRV suggested that artibeus bats were natural reservoir hosts. However, nearly 60 years later experimental infections of Jamaican fruit bats (Artibeus jamaicensis) resulted in fatal disease or clearance, suggesting artibeus bats may not be a reservoir host. To further evaluate the TCRV reservoir host status of artibeus bats, we captured bats of six species in Trinidad for evidence of infection. Bats of all four fruigivorous species captured had antibodies to TCRV nucleocapsid, whereas none of the insectivore or nectarivore species did. Many flat-faced fruit-eating bats (A. planirostris) and great fruit-eating bats (A. literatus) were seropositive by ELISA and western blot to TCRV nucleocapsid antigen, as were two of four Seba's fruit bats (Carollia perspicillata) and two of three yellow-shouldered fruit bats (Sturnira lilium). Serum neutralization tests failed to detect neutralizing antibodies to TCRV from these bats. TCRV RNA was not detected in lung tissues or lung homogenates inoculated onto Vero cells. These data indicate that TCRV or a similar arenavirus continues to circulate among fruit bats of Trinidad but there was no evidence of persistent infection, suggesting artibeus bats are not reservoir hosts.

Indexed as

Serologic TestsAnimalsArenavirusChiropteraGeographySeroepidemiologic StudiesTrinidad and Tobago

Identifiers

PMID28953976
PMCPMC5617188
OpenAlexW2756937580

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.