ArticlePloS one2017
Vascular calcification and cardiac function according to residual renal function in patients on hemodialysis with urination.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Lead augmented vector right T wave and elevated E/e' ratio identify hemodialysis patients at high cardiovascular risk.Kidney research and clinical practice · 2026Article
- Gla-Rich Protein Is Associated with Vascular Calcification, Inflammation, and Mineral Markers in Peritoneal Dialysis Patients.Journal of clinical medicine · 2024Article
- Prediction model for cardiovascular disease risk in hemodialysis patients.International urology and nephrology · 2022Article
- Ultrafiltration Rate, Residual Kidney Function, and Survival Among Patients Treated With Reduced-Frequency Hemodialysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020Article
- Static intra-access pressure ratio and cardiovascular events in patients undergoing haemodialysis.Scientific reports · 2020Article
- Malnutrition, inflammation, progression of vascular calcification and survival: Inter-relationships in hemodialysis patients.PloS one · 2019Observational
- Metabolic and volume status evaluation of hemodialysis patients with and without residual renal function in the long interdialytic interval.Jornal brasileiro de nefrologiaArticle
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD). However, little is known about the effect of residual renal function on vascular calcification and cardiac function in patients on hemodialysis.
methodsThis study was conducted between January 2014 and January 2017. One hundred six patients with residual renal function on maintenance hemodialysis for 3 months were recruited. We used residual renal urea clearance (KRU) to measure residual renal function. First, abdominal aortic calcification score (AACS) and brachial-ankle pulse wave velocity (baPWV) were measured in patients on hemodialysis. Second, we performed echocardiography and investigated new cardiovascular events after study enrollment.
resultsThe median KRU was 0.9 (0.3-2.5) mL/min/1.73m2. AACS (4.0 [1.0-10.0] vs. 3.0 [0.0-8.0], p = 0.05) and baPWV (1836.1 ± 250.4 vs. 1676.8 ± 311.0 cm/s, p = 0.01) were significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than a KRU ≥ 0.9 mL/min/1.73m2. Log-KRU significantly negatively correlated with log-AACS (ß = -0.29, p = 0.002) and baPWV (ß = -0.19, P = 0.05) after factor adjustment. The proportion of left ventricular diastolic dysfunction was significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than with a KRU ≥ 0.9 mL/min/1.73m2 (67.9% vs. 49.1%, p = 0.05). Patients with a KRU < 0.9 mL/min/1.73m2 showed a higher tendency of cumulative cardiovascular events compared to those with a KRU ≥ 0.9 ml/min/1.73m2 (P = 0.08).
conclusionsResidual renal function was significantly associated with vascular calcification and left ventricular diastolic dysfunction in patients on hemodialysis.
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