Evidence map›Paper›PMID 28952925›Full record

ArticleeLife2017

Molecular determinants of permeation in a fluoride-specific ion channel.

Nicholas B Last, Senmiao Sun, Minh C Pham, Christopher Miller

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Membrane Exporters of Fluoride Ion.Annual review of biochemistry · 2021
    Review
  10. Article
  11. Review
  12. A CLC-type FNature structural & molecular biology · 2018
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas B LastDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, United States.
Senmiao SunDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, United States.
Minh C PhamDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, United States.
Christopher MillerDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, United States.ORCID http://orcid.org/0000-0002-0273-8653
Howard Hughes Medical Institute · US

Funding

Mechanisms of Biological Fluoride Resistance ExportersR01GM107023 · NIGMS · BRANDEIS UNIVERSITY · PI MILLER, CHRISTOPHER · 2014 to 2017
$1.1M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM107023
6 · The paper itself

Abstract

Fluoride ion channels of the Fluc family combat toxicity arising from accumulation of environmental F

Indexed as

Amino Acid SubstitutionCrystallography, X-RayDNA Mutational AnalysisFluoridesHydrogen BondingIon ChannelsModels, MolecularProtein ConformationFluoridesIon ChannelsbiophysicsE. colifluorideH-bondion channelpermeationstructural biology

Identifiers

PMID28952925
PMCPMC5636608
OpenAlexW2757302566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.