Evidence map›Paper›PMID 28952162›Full record

ReviewThe British journal of dermatology2017

Risk prediction tools for keratinocyte carcinoma after solid organ transplantation: a review of the literature.

S E Lowenstein, G Garrett, A E Toland, A Jambusaria-Pahlajani, M M Asgari, A Green, E A Engels, S T Arron, National Cancer Institute Keratinocyte Carcinoma Consortium

Abstract readReview
PubMed Publisher
In one paragraph

Review in The British journal of dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Interventions After First Post-Transplant Cutaneous Squamous Cell Carcinoma: A Proposed Decision Framework.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
  5. Review
  6. Keratinocyte Carcinomas: Current Concepts and Future Research Priorities.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

S E LowensteinDepartment of Dermatology, University of California at San Francisco, San Francisco, CA, U.S.A.ORCID http://orcid.org/0000-0001-5598-4711
G GarrettDepartment of Dermatology, University of California at San Francisco, San Francisco, CA, U.S.A.
A E TolandDepartment of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, U.S.A.ORCID http://orcid.org/0000-0002-0271-1792
A Jambusaria-PahlajaniTexas A&M College of Medicine/Baylor Scott & White, Round Rock, TX, U.S.A.
M M AsgariDepartment of Dermatology, Massachusetts General Hospital and Department of Population Medicine, Harvard Medical School, Boston, MA, U.S.A.
A GreenQIMR Berghofer Medical Research Institute, Population Health, Queensland, Australia.
E A EngelsInfections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, U.S.A.
S T ArronDepartment of Dermatology, University of California at San Francisco, San Francisco, CA, U.S.A.ORCID http://orcid.org/0000-0001-5669-0627
National Cancer Institute Keratinocyte Carcinoma Consortium

Funding

Infections, immunity, and inflammation in cancerZIACP010150 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ENGELS, ERIC A · 2009 to 2025
$24.0M
6 · The paper itself

Abstract

Long-term iatrogenic immunosuppression increases the risk of cutaneous malignancies in organ transplant recipients (OTRs), particularly the keratinocyte cancers basal cell carcinoma and cutaneous squamous cell carcinoma (cSCC). cSCC is the most common malignancy in OTRs, with the risk increased to over 65-fold in transplanted patients relative to the general population. There have been very few risk prediction tools developed for accurate determination of the risk of developing keratinocyte cancers in the OTR population. This review summarizes the prediction tools developed to date, and outlines future directions for developing more accurate prediction models that are clinically useful for the transplant physician and dermatologist.

Indexed as

KeratinocytesBasal Cell CarcinomaCarcinoma, Squamous CellEarly Detection of CancerFemaleHumansImmunosuppression TherapyImmunosuppressive AgentsMaleOrgan TransplantationRisk AssessmentRisk FactorsSkin NeoplasmsImmunosuppressive Agents

Identifiers

PMID28952162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.