Evidence map›Paper›PMID 28951990›Full record

Observational studyEuropean journal of nuclear medicine and molecular imaging2018

Clinical utility of FDG PET/CT in acute complicated pyelonephritis-results from an observational study.

Chih-Hsing Wan, Jing-Ren Tseng, Ming-Hsun Lee, Lan-Yan Yang, Tzu-Chen Yen

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Outcome of febrile neutropenic patients treated for bacteriuria in hematology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  7. Article
  8. Non-invasive molecular imaging of kidney diseases.Nature reviews. Nephrology · 2021
    Review
  9. Localization of acute pyelonephritis in pyrexia of unknown origin using FDG PET/CT.Asia Oceania journal of nuclear medicine & biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Chih-Hsing WanDepartment of Nuclear Medicine, Mackay Memorial Hospital at Taipei, No. 92, Section 2, Zhong-shan North road, Zhong-shan District, Taipei, Taiwan, Republic of China.
Jing-Ren TsengDepartment of Nuclear Medicine and Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital at Linkou, No. 5, Fu-Hsing ST., Kwei-Shan, Taoyuan, Taiwan, Republic of China.
Ming-Hsun LeeDivision of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, Republic of China.
Lan-Yan YangBiostatistics Unit, Clinical Trial Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, Republic of China.
Tzu-Chen YenDepartment of Nuclear Medicine and Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital at Linkou, No. 5, Fu-Hsing ST., Kwei-Shan, Taoyuan, Taiwan, Republic of China. yen1110@adm.cgmh.org.tw.ORCID 0000-0002-0352-0277
Chang Gung University · TWChang Gung Memorial Hospital · TWLinkou Chang Gung Memorial Hospital · TWMackay Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute complicated pyelonephritis (ACP) is an upper urinary tract infection associated with coexisting urinary tract abnormalities or medical conditions that could predispose to serious outcomes or treatment failures. Although CT and magnetic resonance imaging (MRI) are frequently used in patients with ACP, the clinical value of

methodsThirty-one adult patients with ACP who underwent FDG PET/CT were examined. FDG PET/CT imaging characteristics, including tracer uptake patterns, kidney volumes, and extrarenal imaging findings, were reviewed in combination with clinical data and conventional imaging results.

resultsOf the 31 patients, 19 (61%) showed focal FDG uptake. The remaining 12 study participants showed a diffuse FDG uptake pattern. After volumetric approximation, the affected kidneys were found to be significantly enlarged. Patients who showed a focal uptake pattern had a higher frequency of abscess formation requiring drainage. ACP patients showing diffuse tracer uptake patterns had a more benign clinical course. Seven patients had suspected extrarenal coinfections, and FDG PET/CT successfully confirmed the clinical suspicion in five cases. FDG PET/CT was as sensitive as CT in identifying the six patients (19%) who developed abscesses. Notably, FDG PET/CT findings caused a modification to the initial antibiotic regimen in nine patients (29%).

conclusionsFDG PET/CT may be clinically useful in the assessment of patients with ACP who have a progressive disease course.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyAcute DiseaseFemaleHumansMaleMiddle AgedPyelonephritisRetrospective StudiesFluorodeoxyglucose F18Acute complicated pyelonephritisCoinfectionFDG PET/CTProgressive disease course

Identifiers

PMID28951990
OpenAlexW2756936185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.