Evidence map›Paper›PMID 28951888›Full record

ArticlemSystems

Systematic Discovery of Archaeal Transcription Factor Functions in Regulatory Networks through Quantitative Phenotyping Analysis.

Cynthia L Darnell, Peter D Tonner, Jordan G Gulli, Scott C Schmidler, Amy K Schmid

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  10. Article
  11. Identifying Components of aFrontiers in microbiology · 2021
    Article
  12. Article
  13. Archaeal transcription.Transcription · 2020
    Review
  14. Article
  15. Article
  16. Gene Expression ofInternational journal of molecular sciences · 2019
    Article
  17. Review
  18. Frontiers in microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cynthia L DarnellDepartment of Biology, Duke University, Durham, North Carolina, USA.
Peter D TonnerDepartment of Biology, Duke University, Durham, North Carolina, USA.
Jordan G GulliDepartment of Biology, Duke University, Durham, North Carolina, USA.
Scott C SchmidlerProgram in Computational Biology and Bioinformatics, Duke University, Durham, North Carolina, USA.
Amy K SchmidDepartment of Biology, Duke University, Durham, North Carolina, USA.
Duke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene regulatory networks (GRNs) are critical for dynamic transcriptional responses to environmental stress. However, the mechanisms by which GRN regulation adjusts physiology to enable stress survival remain unclear. Here we investigate the functions of transcription factors (TFs) within the global GRN of the stress-tolerant archaeal microorganism

Indexed as

Archaeafunctional ANOVAphenomicstranscription factors

Identifiers

PMID28951888
PMCPMC5605881
OpenAlexW2756153974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.