Evidence map›Paper›PMID 28951844›Full record

ArticleIntegrative medicine research2017

Bo-Jeong Pyun, Young Sook Kim, Ik-Soo Lee, Jin Sook Kim

Open access · goldAbstract read
In one paragraph

Article in Integrative medicine research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bo-Jeong PyunKorean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.
Young Sook KimKorean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.
Ik-Soo LeeKorean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.
Jin Sook KimKorean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.
Korea Institute of Oriental Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe loss of retinal pericytes is one of the earliest changes associated with diabetic retinopathy (DR). Chronic hyperglycemia induces apoptosis of these cells, leading to the onset and progression of DR. In this study, we investigated the effects of

methodsThe effects of an ethanol extract of

resultsHG produced cytotoxic effects on HRPs, which showed increased Sp1 expression and ROS levels.

conclusionThese data indicate that HG-mediated induction of Sp1 is one of a number of key signaling pathways involved in HRP apoptosis, and that

Indexed as

apoptosisextracellular signal-regulated kinaseHomonoia ripariahuman retinal pericytesspecificity protein 1

Identifiers

PMID28951844
PMCPMC5605388
OpenAlexW2739652371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.