Evidence map›Paper›PMID 28951767›Full record

ArticleOxidative medicine and cellular longevity2017

Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice.

Ping He, Yafeng Wu, Jianchao Shun, Yaodong Liang, Mingliang Cheng, Yuping Wang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 69 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging.Oxidative medicine and cellular longevity · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Oxidative medicine and cellular longevity · 2020
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ping HeDepartment of Clinical Microbiology and Immunology, Affiliated Hospital of Guizhou Medical University, Guizhou Medical University, Yunyan District, Guiyang City, Guizhou Province 550004, China.
Yafeng WuDepartment of Clinical Microbiology and Immunology, Affiliated Hospital of Guizhou Medical University, Guizhou Medical University, Yunyan District, Guiyang City, Guizhou Province 550004, China.
Jianchao ShunGuizhou Provincial Center for Clinical Laboratory, No. 83 Zhongshandong Road, Guiyang City, China.
Yaodong LiangPublic Health Treatment Center of Guiyang, No. 6 Daying Road, Guiyang City, China.
Mingliang ChengDepartment of Infectious Diseases, Affiliated Hospital of Guizhou Medical University, Guiyang City, Guizhou Province 550004, China.
Yuping WangDepartment of Clinical Microbiology and Immunology, Affiliated Hospital of Guizhou Medical University, Guizhou Medical University, Yunyan District, Guiyang City, Guizhou Province 550004, China.ORCID 0000-0003-2635-5670
Guiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcoholic liver injury leads to serious complication including death. The potential role of baicalin at the transcription level in mice model of alcohol injury is not known yet. In this study, we examined the effect of baicalin against chronic plus binge ethanol model in mice and understanding the mechanism of protection. Liver function, histology, steatosis, inflammation, NF-

Indexed as

AnimalsAnti-Infective AgentsBinge DrinkingChemical and Drug Induced Liver InjuryCytochrome P-450 CYP2E1EthanolFemaleFlavonoidsInflammationLiverMaleMiceNF-E2-Related Factor 2Oxidative StressAnti-Infective Agentsbaicalincytochrome P-450 2E1, mouseCytochrome P-450 CYP2E1EthanolFlavonoidsNfe2l2 protein, mouseNF-E2-Related Factor 2

Identifiers

PMID28951767
PMCPMC5603751
OpenAlexW2748952176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.