Evidence map›Paper›PMID 28951608›Full record

ArticleThe Journal of antibiotics2017

Novel p-terphenyl glycoside with a rare 2,6-dideoxyhexopyranose moiety from Actinomycete strain SF2911 that inhibits cancer cell migration.

Liyan Wang, Menjie Li, Jianqiang Tang, Yinzhi Lin, Kulrawee Sidthipong, Naomi Sumida, Nobuaki Kushida, Kazuo Umezawa

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Liyan WangCollege of Life Sciences and Oceanography, Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen University, Shenzhen, PR China.
Menjie LiCollege of Life Sciences and Oceanography, Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen University, Shenzhen, PR China.
Jianqiang TangCollege of Life Sciences and Oceanography, Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen University, Shenzhen, PR China.
Yinzhi LinDepartment of Molecular Target Medicine, Aichi Medical University School of Medicine, Nagakute, Japan.
Kulrawee SidthipongDepartment of Molecular Target Medicine, Aichi Medical University School of Medicine, Nagakute, Japan.
Naomi SumidaBioscience Institute, Meiji Seika Pharma Co Ltd, Odawara, Japan.
Nobuaki KushidaMeiji Seika Pharma Co, Ltd, Tokyo, Japan.
Kazuo UmezawaDepartment of Molecular Target Medicine, Aichi Medical University School of Medicine, Nagakute, Japan.
Aichi Medical University · JPShenzhen University · CNMeiji (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the course of our search for inhibitors of LPS-induced NO production from microbial strains, an ethyl acetate extract of Actinomycete SF2911, isolated from a soil sample collected in Okinawa Prefecture, Japan, showed the inhibitory activity. The active principle was purified and structure determination led to the isolation of one new compound. Since the structure belongs to the terfestatin family, we named it terfestatin D (1). It was found to inhibit cellular migration of breast carcinoma cells as well as NO production. We herein report the isolation, structure elucidation and biological activities of this new compound.

Indexed as

ActinobacteriaAnimalsAntineoplastic AgentsBiological ProductsCell Line, TumorCell MovementEpithelial CellsFemaleHumansJapanMacrophagesMiceMolecular StructureNitric OxideRAW 264.7 CellsSoil MicrobiologyAntineoplastic AgentsBiological ProductsNitric OxideTerphenyl Compounds

Identifiers

PMID28951608
OpenAlexW2737918838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.