ReviewNature reviews. Gastroenterology & hepatology2017
Expert consensus document: Advances in the physiological assessment and diagnosis of GERD.
Review in Nature reviews. Gastroenterology & hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04255693 (Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence), which is not on this map. Cited by 81 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence
Who cites it
81 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Gastroesophageal disease risk and inhalational exposure a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Gastro-esophageal diagnostic workup before bariatric surgery or endoscopic treatment for obesity: position statement of the International Society of Diseases of the Esophagus.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Guideline
- Thailand guideline 2020 for medical management of gastroesophageal reflux disease.Journal of gastroenterology and hepatology · 2022Guideline
- Efficacy of different endoscopic treatments in patients with gastroesophageal reflux disease: a systematic review and network meta-analysis.Surgical endoscopy · 2021Pooled it
- ACG Clinical Guidelines: Clinical Use of Esophageal Physiologic Testing.The American journal of gastroenterology · 2020Guideline
- Editorial: Do We Need to Adapt GERD Metrics Based on the Population Being Evaluated?Alimentary pharmacology & therapeutics · 2026Article
- Inter-Observer Variability of Gerd-Related Metrics on High-Resolution Manometry and Calculation of the Milan Score.Neurogastroenterology and motility · 2026Article
- Rethinking Long-Term PPI Therapy in GERD: A Narrative Review from a Microbial Ecology Perspective Beyond Acid Suppression.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Potassium-competitive acid blockers for the management of gastroesophageal reflux disease.Nature reviews. Gastroenterology & hepatology · 2026Article
- Upper gastrointestinal endoscopy in patients with gastroesophageal reflux disease symptoms: Correlating endoscopic findings with symptoms and pH-impedance results.World journal of gastrointestinal endoscopy · 2026Article
- The Immune Architecture of Eosinophilic Esophagitis: Mechanisms, Therapeutic Targets, and Precision Management.ImmunoTargets and therapy · 2026Review
- Gastrointestinal Symptoms in Systemic Sclerosis: Prevalence and Severity across Disease Subtypes and Autoantibody Profiles.Acta medica Lituanica · 2026Article
- Association of gastroesophageal reflux disease with small intestinal bacterial overgrowth: a case-control study.BMC gastroenterology · 2025Article
- Demographic and Manometric Variables Can Independently Predict Gastroesophageal Reflux Disease: The AGES-D Score.The Korean journal of helicobacter and upper gastrointestinal research · 2025Article
- A Cross-Sectional Study on Gastric Diseases and FGIDs in Bangladesh: Insights Into Causes, Symptoms, and Medications.Health science reports · 2025Article
- Insight into global burden of gastroesophageal reflux disease: Understanding its reach and impact.World journal of gastrointestinal pharmacology and therapeutics · 2025Review
- The diagnostic criteria for psychosomatic research-revised (DCPR-R) in a National China multicenter cohort of patients with irritable bowel syndrome and overlapping gastroesophageal reflux disease.BMC gastroenterology · 2025Article
- A Low-Friction Capsule Robot with Drive-Control-Sensing Integration for Gastrointestinal Lesion Detection.Research (Washington, D.C.) · 2025Article
- Global temporal trends and projections of gastroesophageal reflux disease prevalence: Age-period-cohort analysis 2021.PloS one · 2025Article
- The Clinical Spectrum of Gastroesophageal Reflux Disease: Facts and Fictions.Visceral medicine · 2024Review
21 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
GERD is a common condition worldwide. Key mechanisms of disease include abnormal oesophagogastric junction structure and function, and impaired oesophageal clearance. A therapeutic trial of acid-suppressive PPI therapy is often the initial management, with endoscopy performed in the setting of alarm symptoms and to exclude other conditions. If symptoms persist and endoscopy does not reveal evidence of GERD, oesophageal function tests are performed, including oesophageal manometry and ambulatory reflux monitoring. However, reflux episodes can be physiological, and some findings on endoscopy and manometry can be encountered in asymptomatic individuals without GERD symptoms. The diagnosis of GERD on the basis of functional oesophageal testing has been previously reported, but no updated expert recommendations on indications and the interpretation of oesophageal function testing in GERD has been made since the Porto consensus over a decade ago. In this Consensus Statement, we aim to describe modern oesophageal physiological tests and their analysis with an emphasis on establishing indications and consensus on interpretation parameters of oesophageal function testing for the evaluation of GERD in clinical practice. This document reflects the collective conclusions of the international GERD working group, incorporating existing data with expert consensus opinion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.