Evidence map›Paper›PMID 28951563›Full record

ArticleScientific reports2017

A Printed Multicomponent Paper Sensor for Bacterial Detection.

M Monsur Ali, Christine L Brown, Sana Jahanshahi-Anbuhi, Balamurali Kannan, Yingfu Li, Carlos D M Filipe, John D Brennan

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Paper-based sensors for bacteria detection.Nature reviews bioengineering · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Biosensing with DNAzymes.Chemical Society reviews · 2021
    Review
  14. Review
  15. Detection ofFrontiers in microbiology · 2021
    Article
  16. Nucleic Acids Analysis.Science China. Chemistry · 2021
    Review
  17. Article
  18. Review
  19. Article
  20. A Simple DNAzyme-Based Fluorescent Assay for Klebsiella pneumoniae.Chembiochem : a European journal of chemical biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M Monsur AliBiointerfaces Institute, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 0A3, Canada.
Christine L BrownDepartment of Chemical Engineering, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 4L7, Canada.
Sana Jahanshahi-AnbuhiDepartment of Chemical Engineering, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 4L7, Canada.
Balamurali KannanBiointerfaces Institute, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 0A3, Canada.
Yingfu LiDepartment of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0002-7533-6743
Carlos D M FilipeDepartment of Chemical Engineering, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 4L7, Canada. filipec@mcmaster.ca.
John D BrennanBiointerfaces Institute, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 0A3, Canada. brennanj@mcmaster.ca.ORCID 0000-0003-3461-9824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a simple all-in-one paper-based sensor for E. coli detection using a composite ink made of a fluorogenic DNAzyme probe for bacterial recognition and signal generation, lysozyme that lyses whole bacterial cells, and pullulan/trehalose sugars that stabilize printed bioactive molecules. The paper sensor is capable of producing a fluorescence signal as a readout within 5 minutes upon contacting E. coli, can achieve a limit of detection of 100 cells/mL, in a variety of sample matrixes, without sample enrichment, and remains stable for at least 6 months when stored at ambient temperature. Therefore, this simple paper sensor provides rapid bacterial testing on site, and can be shipped and stored under ambient conditions to benefit users living in resource-limited regions.

Indexed as

PaperBacteriaBiosensing TechniquesBiotechnologyDNA, CatalyticEnzymes, ImmobilizedFluorescenceGlucansLimit of DetectionMolecular ProbesMuramidaseTrehaloseDNA, CatalyticEnzymes, ImmobilizedGlucansMolecular ProbesMuramidasepullulanTrehalose

Identifiers

PMID28951563
PMCPMC5615064

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.