Evidence map›Paper›PMID 28951529›Full record

ArticleGenetics2017

Yadu Gautam, Mekibib Altaye, Changchun Xie, Tesfaye B Mersha

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Admixture Mapping in African Americans Identifies New Risk Loci for HCV-Related Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yadu GautamDivision of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Ohio 45229-3026.
Mekibib AltayeDivision of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Ohio 45229-3026.
Changchun XieDivision of Biostatistics and Bioinformatics, Department of Environmental Health, University of Cincinnati, Ohio 45229-3026.
Tesfaye B MershaDivision of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Ohio 45229-3026 tesfaye.mersha@cchmc.org.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Unraveling ancestry and environmental exposure interactions in childhood asthmaR01HL132344 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2016 to 2020
$3.4M
Ancestry-Environmental Exposure Interactions and Asthma Risk in Admixed PopulationR03HL133713 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2016 to 2017
$156k
NCATS NIH HHS UL1 TR001425NHLBI NIH HHS R01 HL132344NHLBI NIH HHS R03 HL133713
6 · The paper itself

Abstract

Admixed populations result from recent admixture of two or more ancestral populations with divergent allele frequencies. The genome of each admixed individual is a mosaic of haplotypes inherited from the ancestral populations. Despite the substantial work to assess power and sample size requirements for association mapping in genetically homogeneous populations of European ancestry, power and sample size estimation methods for mapping genes in genetically heterogeneous admixed populations such as African Americans are lacking. Admixture mapping is a method that traces the ancestral origin of disease-susceptibility genetic loci in the admixed population. We developed

Indexed as

Genetic LociSoftwareBlack or African AmericanChromosome MappingGene FrequencyGenotypeHumansPopulationSample Sizeadmixed populationAdmixPoweradmixture mappingsample sizestatistical power

Identifiers

PMID28951529
PMCPMC5676228
OpenAlexW2759300470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.