Evidence map›Paper›PMID 28950912›Full record

Observational studyAddiction science & clinical practice2017

Alcohol consumption patterns and HIV viral suppression among persons receiving HIV care in Florida: an observational study.

R L Cook, Z Zhou, N E Kelso-Chichetto, J Janelle, J P Morano, C Somboonwit, W Carter, G E Ibanez, N Ennis, C L Cook and 3 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Addiction science & clinical practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04054466 (Effectiveness of the Nursing Counseling to the Change of Behavior of Alcohol Consumption in Patients Receiving HAART), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04054466 nacompletednot on this mapstarted 2018, after this paper: background citation

Effectiveness of the Nursing Counseling to the Change of Behavior of Alcohol Consumption in Patients Receiving HAART

TypeinterventionalSponsorUniversidad Peruana Cayetano HerediaRan2018 to 2020Enrolled233ConditionsHIV, Alcohol DrinkingArmsNursing Counseling in the change of Alcohol Consumption Behavior in patients receiving HAART, Habitual Counseling
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

R L CookDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, PO Box 100231, Gainesville, FL, 32610, USA. cookrl@ufl.edu.ORCID 0000-0002-7770-3754
Z ZhouDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, PO Box 100231, Gainesville, FL, 32610, USA.
N E Kelso-ChichettoDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, PO Box 100231, Gainesville, FL, 32610, USA.
J JanelleDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, PO Box 100231, Gainesville, FL, 32610, USA.
J P MoranoDivision of Infectious Diseases and International Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
C SomboonwitDepartment of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
W CarterFlorida Department of Health, Orange County Office of Clinical Services, Disease Investigation and Research, Orlando, FL, USA.
G E IbanezDepartment of Epidemiology, Florida International University, Miami, FL, USA.
N EnnisDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
C L CookDepartment of Family, Community, and Health System Science, College of Nursing, University of Florida, Gainesville, FL, USA.
R A CohenDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
B BrumbackDepartment of Biostatistics, University of Florida, Gainesville, FL, USA.
K BryantNational Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
University of Florida · USUniversity of Florida Health · USUniversity of South Florida · USFlorida Department of Health in Orange County · USFlorida International University · USNational Institute on Alcohol Abuse and Alcoholism · US

Funding

Virology CoreP01AA019072 · NIAAA · BROWN UNIVERSITY · PI KAHLER, CHRISTOPHER W. · 2010 to 2024
$19.7M
Mechanisms of Behavior Change Resource Core for Alcohol-HIV InterventionsU24AA022003 · NIAAA · BROWN UNIVERSITY · PI KAHLER, CHRISTOPHER W. · 2012 to 2020
$5.9M
Southern HIV and Alcohol Research Consortium Administrative and Research Support CoreU24AA022002 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L · 2012 to 2022
$5.5M
Feasibility of SBIRT for Underserved HIV+ Adults 50+ in Primary Care SettingsK23DA039769 · NIDA · UNIVERSITY OF FLORIDA · PI ENNIS, NICOLE · 2016 to 2020
$769k
NIAAA NIH HHS P01 AA019072NIAAA NIH HHS U24 AA022002NIAAA NIH HHS U24 AA022003NIDA NIH HHS K23 DA039769
6 · The paper itself

Abstract

backgroundAlcohol consumption has been associated with poor antiretroviral therapy (ART) adherence but less is known about its relationship to HIV viral suppression, or whether certain drinking patterns have a stronger association than others. The objectives of this study were to determine the association of different patterns of alcohol consumption to HIV viral suppression and ART adherence, and to determine whether any associations of alcohol with HIV viral suppression were mediated by poor ART adherence.

methodsThis observational study used baseline data from 619 HIV+ participants, recruited across 8 clinical and community settings across Florida as part of the Florida Cohort from 2014 to 2016. Alcohol consumption was measured by self-report, and grouped into four categories: heavy drinking (>7/week for women or >14 drinks/week for men); binge, but not heavy drinking (≥4 or >5 drinks/occasion for women and men, respectively), low level drinking (neither heavy nor binge), and abstinence. Serum HIV RNA measurements were obtained from statewide HIV surveillance data, and durable viral suppression was defined as achieving HIV viral suppression (<200 copies/ml) at every assessment in the past 12 months.

resultsThe majority of the 619 participants were male (63%) and aged 45 or greater (65%). The proportion of participants with heavy, binge, low-level drinking and abstinence was 9, 25, 37 and 30%, respectively. Optimal ART adherence (≥95%) was reported by 68%, and 60% achieved durable viral suppression. In multivariable analysis controlling for demographic factors, drug use, and homelessness, heavy drinking (compared to abstinence) was associated with increased odds of failing to achieve durable viral suppression (OR 2.16, 95% CI 1.08-4.32) whereas binge drinking alone was not significantly associated with this outcome (OR 1.04, 95% CI 0.64-1.70). Both heavy drinking and binge drinking were significantly associated with suboptimal ART adherence. Mediation analyses suggested that only a small proportion of the relationship between heavy drinking and suboptimal viral suppression was due to poor ART adherence.

conclusionsExceeding weekly recommended levels of alcohol consumption (heavy drinking) was significantly associated with poor HIV viral suppression and ART non-adherence, while binge drinking was associated with suboptimal ART adherence in this sample. Clinicians should attempt to address heavy drinking in their patients with HIV.

Indexed as

Drug MonitoringHealth BehaviorSustained Virologic ResponseAdultAlcohol DrinkingAnti-HIV AgentsFemaleFloridaHIV InfectionsHumansMaleMiddle AgedPovertySocioeconomic FactorsAnti-HIV AgentsAlcohol consumptionART adherenceBinge drinkingHIVViral suppression

Identifiers

PMID28950912
PMCPMC5615807
OpenAlexW2752611082

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.