Evidence map›Paper›PMID 28950871›Full record

SynthesisEnvironmental health : a global access science source2017

Lung cancer mortality of residents living near petrochemical industrial complexes: a meta-analysis.

Cheng-Kuan Lin, Huei-Yang Hung, David C Christiani, Francesco Forastiere, Ro-Ting Lin

Erratum issuedAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Environmental health : a global access science source, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Article
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  8. Article
  9. An Exploratory Investigation of Government Air Monitoring Data after Hurricane Harvey.International journal of environmental research and public health · 2022
    Article
  10. Article
  11. Using an Integrated Social Cognition Model to Explain Green Purchasing Behavior among Adolescents.International journal of environmental research and public health · 2021
    Article
  12. Cancer Incidence Trends in the Oil Shale Industrial Region in Estonia.International journal of environmental research and public health · 2020
    Article
  13. Article
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  15. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cheng-Kuan LinDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Building 1, Room 1401, Boston, MA, 02115, USA.
Huei-Yang HungDepartment of General Medicine, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, Kaohsiung, 807, Taiwan.
David C ChristianiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Building 1, Room 1401, Boston, MA, 02115, USA.
Francesco ForastiereDepartment of Epidemiology Lazio Regional Health Service, Via Cristoforo Colombo, 112, Rome, Italy.
Ro-Ting LinDepartment of Occupational Safety and Health, College of Public Health, China Medical University, 91 Hsueh-Shih Road, Taichung, 40402, Taiwan. roting@mail.cmu.edu.tw.ORCID 0000-0002-2687-203X

Funding

Statistical Methods for Analysis of Massive Genetic and Genomic Data in Cancer ResearchR35CA197449 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI XIHONG LIN · 2015 to 2026
$10.9M
NCI NIH HHS R35 CA197449
6 · The paper itself

Abstract

backgroundLung cancer, as the leading cause of cancer mortality worldwide, has been linked to environmental factors, such as air pollution. Residential exposure to petrochemicals is considered a possible cause of lung cancer for the nearby population, but results are inconsistent across previous studies. Therefore, we performed a meta-analysis to estimate the pooled risk and to identify possible factors leading to the heterogeneity among studies.

methodsThe standard process of selecting studies followed the Cochrane meta-analysis guideline of identification, screening, eligibility, and inclusion. We assessed the quality of selected studies using the Newcastle-Ottawa scale. Reported point estimates and 95% confidence intervals were extracted or calculated to estimate the pooled risk. Air quality standards were summarized and treated as a surrogate of exposure to air pollution in the studied countries. Funnel plots, Begg's test and Egger's test were conducted to diagnose publication bias. Meta-regressions were performed to identify explanatory variables of heterogeneity across studies.

resultsA total of 2,017,365 people living nearby petrochemical industrial complexes (PICs) from 13 independent studied population were included in the analysis. The pooled risk of lung cancer mortality for residents living nearby PICs was 1.03-fold higher than people living in non-PIC areas (95% CI = 0.98-1.09), with a low heterogeneity among studies (I

conclusionsOur meta-analysis gathering current evidence suggests only a slightly higher risk of lung cancer mortality among residents living nearby PICs, albeit such association didn't receive statistically significance. Reasons for higher risks of early residential exposure to PICs might be attributable to the lack of or less stringent air pollution regulations.

Indexed as

Environmental ExposureOil and Gas IndustryAir PollutantsAir PollutionHumansLung NeoplasmsPetroleum PollutionResidence CharacteristicsRisk FactorsAir PollutantsLung cancerLung neoplasmMeta-analysisOil and gas industryPetrochemicalPetroleumRefinery

Identifiers

PMID28950871
PMCPMC5615452

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.