ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2017
Hyper-attenuating brain lesions on CT after ischemic stroke and thrombectomy are associated with final brain infarction.
Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 20 citations in OpenAlex.
- Noncontrast CT-based habitat analysis for differentiating hemorrhagic transformation from contrast extravasation after endovascular therapy of acute ischemic stroke.European radiology experimental · 2026Article
- Contrast enhancement after mechanical thrombectomy: clinical correlations and impact on outcomes.Acta neurologica Belgica · 2025Article
- Differential impact of deep intraparenchymal hyperdensities versus subarachnoid/cortical hyperdensities on futile reperfusion after mechanical thrombectomy: a propensity score-matched study.Frontiers in neurology · 2025Article
- Risk factors and impact on outcomes of high-density shadow on immediate cerebral CT after successful interventional recanalization in acute ischemic stroke with large vessel occlusion.Frontiers in neurology · 2025Article
- Incidence, Risk Factors, and Clinical Implications of Subarachnoid Hyperdensities on Flat-Panel Detector CT following Mechanical Thrombectomy in Patients with Anterior Circulation Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2024Article
- Post-endovascular treatment, blood-brain barrier disruption, predicts patient outcomes better than pre-treatment status.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Contrast Staining in Noninfarcted Tissue after Endovascular Treatment of Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2024Article
- Contrast enhancement by location and volume is associated with long-term outcome after thrombectomy in acute ischemic stroke.Scientific reports · 2022Article
- Frontal lobe hemorrhage in a patient with lenticulostriate artery territory infarction and middle cerebral artery occlusion after recanalization: a case study and literature analysis.Quantitative imaging in medicine and surgery · 2022Article
- Hyperattenuations on flat-panel computed tomography after successful recanalization of mechanical thrombectomy for anterior circulation occlusion.Quantitative imaging in medicine and surgery · 2022Article
- Post-ASPECTS based on hyperdensity in NCCT immediately after thrombectomy is an ultra-early predictor of hemorrhagic transformation and prognosis.Frontiers in neurology · 2022Article
- Value of high-density sign on CT images after mechanical thrombectomy for large vessel occlusion in predicting hemorrhage and unfavorable outcome.The neuroradiology journal · 2021Article
- A New Classification System for Postinterventional Cerebral Hyperdensity: The Influence on Hemorrhagic Transformation and Clinical Prognosis in Acute Stroke.Neural plasticity · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Purpose Hyper-attenuating lesions, or contrast staining, on a non-contrast brain computed tomography (NCCT) scan have been investigated as a predictor for hemorrhagic transformation after endovascular treatment of acute ischemic stroke (AIS). However, the association of hyper-attenuating lesions and final ischemic areas are poorly investigated in this setting. The aim of the present study was to assess correlations between hyper-attenuating lesions and final brain infarcted areas after thrombectomy for AIS. Methods Data from patients with AIS of the anterior circulation who underwent endovascular treatment were retrospectively assessed. Images of the brain NCCT scans were analyzed in the first hours and late after treatment. The hyper-attenuating areas were compared to the final ischemic areas using the Alberta Stroke Program Early CT Score (ASPECTS). Results Seventy-one of the 123 patients (65.13%) treated were included. The association between the hyper-attenuating region in the post-thrombectomy CT scan and final brain ischemic area were sensitivity (58.3% to 96.9%), specificity (42.9% to 95.6%), positive predictive values (71.4% to 97.7%), negative predictive values (53.8% to 79.5%), and accuracy values (68% to 91%). The highest sensitivity values were found for the lentiform (96.9%) and caudate nuclei (80.4%) and for the internal capsule (87.5%), and the lowest values were found for the M1 (58.3%) and M6 (66.7%) cortices. Conclusions Hyper-attenuating lesions on head NCCT scans performed after endovascular treatment of AIS may predict final brain infarcted areas. The prediction appears to be higher in the deep brain regions compared with the cortical regions.
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