Evidence map›Paper›PMID 28950152›Full record

ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2017

Frontal EEG asymmetry and later behavior vulnerability in infants with congenital visual impairment.

Michelle A O'Reilly, Joe Bathelt, Elena Sakkalou, Hanna Sakki, Alison Salt, Naomi J Dale, Michelle de Haan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Clinical Implication of Maumgyeol Basic Service-the 2 Channel Electroencephalography and a Photoplethysmogram-based Mental Health Evaluation Software.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Michelle A O'ReillyClinical Neurosciences Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London, UK.
Joe BatheltMRC Cognition & Brain Sciences Unit, University of Cambridge, UK; Cognitive Neuroscience and Neuropsychiatry Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, UK.
Elena SakkalouClinical Neurosciences Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London, UK.
Hanna SakkiClinical Neurosciences Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London, UK.
Alison SaltClinical Neurosciences Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London, UK; Developmental Vision Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
Naomi J DaleClinical Neurosciences Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London, UK; Developmental Vision Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK. Electronic address: n.dale@ucl.ac.uk.
Michelle de HaanCognitive Neuroscience and Neuropsychiatry Section, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, UK.
University College London · GBGreat Ormond Street Hospital · GBMRC Cognition and Brain Sciences Unit · GB

Funding

Medical Research Council G1002276Medical Research Council MC_UP_A060_1103Medical Research Council MC_UU_00005/2
6 · The paper itself

Abstract

objectiveYoung children with congenital visual impairment (VI) are at increased risk of behavioral vulnerabilities. Studies on 'at risk' populations suggest that frontal EEG asymmetry may be associated with behavioral risk. We investigated frontal asymmetry at 1year (Time 1), behavior at 2years (Time 2) and their longitudinal associations within a sample of infants with VI. Frontal asymmetry in the VI sample at 1year was also compared cross-sectionally to an age-matched typically sighted (TS) group.

methodsAt Time 1, 22 infants with VI and 10 TS infants underwent 128-channel EEG recording. Frontal asymmetry ratios were calculated from power spectral density values in the alpha frequency band. At Time 2, Achenbach Child Behavior Checklist data was obtained for the VI sample.

results63.6% of the VI sample and 50% of the TS sample showed left frontal asymmetry; no significant difference in frontal asymmetry was found between the two groups. 22.7% of the VI sample had subclinical to clinical range 'internalizing' behavior difficulties. Greater left frontal asymmetry at one year was significantly associated with greater emotionally reactive scores at two years within the VI sample (r=0.50, p=0.02).

conclusionsLeft frontal asymmetry correlates with later behavior risk within this vulnerable population. SIGNIFICANCE: These findings make an important first contribution regarding the utility of frontal EEG asymmetry as a method to investigate risk in infants with VI.

Indexed as

Child Behavior DisordersChild, PreschoolCross-Sectional StudiesElectroencephalographyFemaleFrontal LobeFunctional LateralityHumansInfantMaleVision DisordersBehaviorChildrenFrontal EEG asymmetryInfancyVisionVision disordersVisual impairment

Identifiers

PMID28950152
PMCPMC6609275
OpenAlexW2752778190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.