Evidence map›Paper›PMID 28950095›Full record

ArticleDevelopmental cell2017

TrkA Bumps into Its Future Self.

Kelly Barford, Austin Keeler, Christopher Deppmann, Bettina Winckler

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nerves in cancer.Nature reviews. Cancer · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Kelly BarfordDepartment of Cell Biology, University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908-0732, USA.
Austin KeelerDepartment of Biology, University of Virginia, Physical Life Sciences Building, 90 Geldard Drive, Charlottesville, VA 22903, USA.
Christopher DeppmannDepartment of Cell Biology, University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908-0732, USA; Department of Biology, University of Virginia, Physical Life Sciences Building, 90 Geldard Drive, Charlottesville, VA 22903, USA.
Bettina WincklerDepartment of Cell Biology, University of Virginia, 1340 Jefferson Park Avenue, Charlottesville, VA 22908-0732, USA. Electronic address: bwinckler@virginia.edu.

Funding

Organization and Function of Neuronal EndosomesR01NS083378 · NINDS · UNIVERSITY OF VIRGINIA · PI Bettina R Winckler · 2013 to 2026
$5.2M
Novel Endosomal Pathways Underlying NGF/TrkA Dependent Dendrite DevelopmentF31NS098621 · NINDS · UNIVERSITY OF VIRGINIA · PI BARFORD, KELLY ANN · 2016 to 2018
$44k
NINDS NIH HHS F31 NS098621
6 · The paper itself

Abstract

In neurons, correct targeting of receptors to the axon is critical for cell survival and circuit formation. In this issue of Developmental Cell, Yamashita et al. (2017) report that the ER-resident phosphatase PTP1B is required to prime TrkA for axonal transport.

Indexed as

Axonal TransportReceptor, trkAAxonsCell SurvivalHumansNeuronsReceptor, trkA

Identifiers

PMID28950095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.