Evidence map›Paper›PMID 28949518›Full record

ArticleInorganic chemistry2017

Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands.

Lars Kohler, Leona Nease, Pascal Vo, Jenna Garofolo, David K Heidary, Randolph P Thummel, Edith C Glazer

Abstract read
In one paragraph

Article in Inorganic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Ruthenium-based PACT agents based on bisquinoline chelates: synthesis, photochemistry, and cytotoxicity.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lars KohlerDepartment of Chemistry, University of Houston , 112 Fleming Building, Houston, Texas 77204-5003, United States.
Leona NeaseDepartment of Chemistry, University of Kentucky , Lexington, Kentucky 40506, United States.
Pascal VoDepartment of Chemistry, University of Houston , 112 Fleming Building, Houston, Texas 77204-5003, United States.
Jenna GarofoloDepartment of Chemistry, University of Kentucky , Lexington, Kentucky 40506, United States.
David K HeidaryDepartment of Chemistry, University of Houston , 112 Fleming Building, Houston, Texas 77204-5003, United States.
Randolph P ThummelDepartment of Chemistry, University of Houston , 112 Fleming Building, Houston, Texas 77204-5003, United States.ORCID http://orcid.org/0000-0001-9586-786X
Edith C GlazerDepartment of Chemistry, University of Kentucky , Lexington, Kentucky 40506, United States.ORCID http://orcid.org/0000-0002-0190-7742

Funding

Light-responsive ruthenium compounds for applications in diseaseR01GM107586 · NIGMS · UNIVERSITY OF KENTUCKY · PI GLAZER, EDITH C · 2014 to 2019
$1.7M
NIGMS NIH HHS R01 GM107586
6 · The paper itself

Abstract

Light-activated compounds are powerful tools and potential agents for medical applications, as biological effects can be controlled in space and time. Ruthenium polypyridyl complexes can induce cytotoxic effects through multiple mechanisms, including acting as photosensitizers for singlet oxygen (

Indexed as

2,2'-DipyridylChelating AgentsCoordination ComplexesDNA AdductsDNA BreaksDNA ReplicationHL-60 CellsHumansLigandsLightMethylationProtein BiosynthesisPyrimidinesRutheniumSinglet OxygenStructure-Activity Relationship2,2'-DipyridylChelating AgentsCoordination ComplexesDNA AdductsLigandsPyrimidinesRutheniumSinglet Oxygen

Identifiers

PMID28949518
PMCPMC6040668

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.