Evidence map›Paper›PMID 28949292›Full record

ArticleeLife2017

Mechanism of environmentally driven conformational changes that modulate H-NS DNA-bridging activity.

Ramon A van der Valk, Jocelyne Vreede, Liang Qin, Geri F Moolenaar, Andreas Hofmann, Nora Goosen, Remus T Dame

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. A functional interplay ofMicrobiology spectrum · 2026
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  12. Nucleoid-associated proteins: molecular mechanisms in microbial adaptation.World journal of microbiology & biotechnology · 2025
    Review
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ramon A van der ValkLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.
Jocelyne VreedeComputational Chemistry, Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, Netherlands.
Liang QinLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.
Geri F MoolenaarLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.
Andreas HofmannInstitute for Theoretical Physics, University of Heidelberg, Heidelberg, Germany.
Nora GoosenLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.
Remus T DameLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.ORCID http://orcid.org/0000-0001-9863-1692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria frequently need to adapt to altered environmental conditions. Adaptation requires changes in gene expression, often mediated by global regulators of transcription. The nucleoid-associated protein H-NS is a key global regulator in

Indexed as

DNAEscherichia coli ProteinsFimbriae ProteinsMolecular Dynamics SimulationProtein BindingProtein ConformationDNAEscherichia coli ProteinsFimbriae ProteinsFimG protein, E colibacterial chromatinbiophysicschromosomesE. coligenesHhaH-NSnucleoidstructural biologyYdgT

Identifiers

PMID28949292
PMCPMC5647153

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.