ArticleLa Radiologia medica2018
Correlation between voxel-wise enhancement parameters on DCE-MRI and pathological prognostic factors in invasive breast cancers.
Article in La Radiologia medica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Breast Cancer Subtypes and Quantitative Magnetic Resonance Imaging: A Systemic Review.Life (Basel, Switzerland) · 2022Review
- Article
- Apparent diffusion coefficient magnetic resonance imaging (ADC-MRI) in the axillary breast cancer lymph node metastasis detection: a narrative review.Gland surgery · 2020Review
- Use of MRI for Personalized Treatment of More Aggressive Tumors.Radiology · 2020Article
- Relationship between histogram metrics of pharmacokinetic parameters of DCE-MRI and histological phenotype in breast cancer.Translational cancer research · 2020Article
- Preoperative loco-regional staging of invasive lobular carcinoma with contrast-enhanced digital mammography (CEDM).La Radiologia medica · 2019Article
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Authors and funding
9 authors.
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Abstract
purposeTo investigate the correlation between enhancement parameters on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and pathologic prognostic factors in invasive breast cancers (BCs). MATERIALS AND
methodsA total of 25 invasive BCs were included: 22 invasive ductal, 2 invasive lobular and 1 invasive mucinous. The tumor volume was segmented using a semi-automatic software (Olea Sphere). The following voxel-wise enhancement parameters were extracted: (1) time to peak enhancement; (2) signal intensity at peak (SIP); (3) peak enhancement percentage (PEP); (4) post-initial enhancement percentage (PIEP). The following pathological prognostic factors were considered for potential correlation: tumor (pT) and nodal (pN) stage, grading, perivascular/perineural invasion, estrogen/progesterone receptor status, Ki-67 proliferation, and HER2 expression. Spearman and Pearson correlation coefficients were calculated according with type of variable and data distribution.
resultsTumor volume was 2.8 ± 2.0 cm
conclusionIn invasive BCs, DCE-MRI voxel-wise enhancement parameters correlated with HER2, pT, and pN.
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