Evidence map›Paper›PMID 28948392›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Impact of body composition on outcome in patients with early breast cancer.

Elise Deluche, Sophie Leobon, Jean Claude Desport, Laurence Venat-Bouvet, Julie Usseglio, Nicole Tubiana-Mathieu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Prevalence and clinical implications of sarcopenia in breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  9. Muscle quality during cancer treatment and associations with health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  13. Body Composition with Dual-Energy X-Ray Absorptiometry and Bioelectrical Impedance Analysis in Breast Cancer Survivors.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2019
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  14. Baseline fdg pet/ct-derived tumor burden and host metabolic activity predict complete metabolic response to neoadjuvant chemotherapy in ınvasive ductal breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  19. UsingEuropean journal of nuclear medicine and molecular imaging · 2026
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elise DelucheDepartment of Medical Oncology, University Hospital, 2 Avenue Martin Luther King, 87042, Limoges Cedex, France. elise.deluche@chu-limoges.fr.
Sophie LeobonDepartment of Medical Oncology, University Hospital, 2 Avenue Martin Luther King, 87042, Limoges Cedex, France.
Jean Claude DesportNutrition Unit, University Hospital, 87042, Limoges, France.
Laurence Venat-BouvetDepartment of Medical Oncology, University Hospital, 2 Avenue Martin Luther King, 87042, Limoges Cedex, France.
Julie UsseglioDepartment of Medical Oncology, University Hospital, 2 Avenue Martin Luther King, 87042, Limoges Cedex, France.
Nicole Tubiana-MathieuDepartment of Medical Oncology, University Hospital, 2 Avenue Martin Luther King, 87042, Limoges Cedex, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated the impact of body composition on outcomes of patients with early breast cancer. Skeletal muscle mass, visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and muscle fat infiltration or inter-muscular adipose tissue areas (IMAT), obtained by computed tomography (CT), were assessed.

methodsA total of 119 female patients who had breast cancer were included in this retrospective study. The total skeletal muscle and fat tissue areas were evaluated in two adjacent axial slices obtained at the third lumbar vertebra by CT used for disease staging. The women were assigned to either a sarcopenia or non-sarcopenia group based on their skeletal muscle index (cut-off 41.0 cm

resultsAmong the 119 evaluable patients, 58 were sarcopenic (48.8%), 55 (46.2%) had a high VAT/SAT ratio, and 62 (52.1%) had a high IMAT index. Median follow-up was 52.4 months. Multivariate analysis revealed sarcopenia and IMAT index as independent prognostic factors for disease-free survival (p = 0.02 and p = 0.04, respectively) and overall survival (p = 0.05 and p = 0.02, respectively). BMI was not significantly associated with disease-free survival, but a trend was observed (p = 0.09).

conclusionsSarcopenia and IMAT index are independent prognostic factors in early breast cancer; therefore, assessing body composition could be a simple and useful approach to integrate into patient management.

Indexed as

AdultAgedAged, 80 and overBody CompositionBreast NeoplasmsDisease-Free SurvivalFemaleHumansMiddle AgedPrognosisRetrospective StudiesSarcopeniaYoung AdultBody compositionEarly breast cancerPrognosisSarcopenia

Identifiers

PMID28948392
PMCPMC5785600

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.