Evidence map›Paper›PMID 28948181›Full record

ArticleOpen forum infectious diseases2017

Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection.

Christoph Boesecke, Patrick Ingiliz, Florian Berger, Thomas Lutz, Knud Schewe, Julian Schulze Zur Wiesch, Axel Baumgarten, Stefan Christensen, Jürgen K Rockstroh, Stefan Mauss and 1 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Unsuccessful Direct Acting Antiviral Hepatitis C Treatment Among People With HIV: Findings From an International Cohort.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christoph BoeseckeUniversity Hospital Bonn, Germany.
Patrick IngilizCenter for Infectiology Berlin, Germany.
Florian BergerCenter for HIV and Hepatogastroenterology, Düsseldorf, Germany.
Thomas LutzInfektiologikum, Frankfurt, Germany.
Knud ScheweInfektionsmedizinisches Centrum Hamburg, Germany.
Julian Schulze Zur WieschGerman Centre for Infection Research (DZIF), Braunschweig, Germany.
Axel BaumgartenCenter for Infectiology Berlin, Germany.
Stefan ChristensenCIM Infectious Diseases, Münster, Germany.
Jürgen K RockstrohUniversity Hospital Bonn, Germany.
Stefan MaussCenter for HIV and Hepatogastroenterology, Düsseldorf, Germany.
GECCO Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current hepatitis C virus (HCV) treatment guidelines recommend treating HCV/human immunodeficiency virus (HIV)-coinfected individuals similar to HCV-monoinfected individuals. Recently inferior response rates to direct acting antiviral (DAA) therapy in HCV/HIV coinfection have been reported. Our German hepatitis C cohort (GECCO) cohort data show that coinfected patients with liver cirrhosis are less likely to achieve viral eradication.

Indexed as

chronic hepatitis CDAAHCV/HIV coinfectionHCV treatment

Identifiers

PMID28948181
PMCPMC5604144

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.