ArticleOpen forum infectious diseases2017
Evidence of High Mortality and Increasing Burden of Sepsis in a Regional Sample of the New Zealand Population.
Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis.Intensive care medicine · 2020Pooled it
- Association Between Community-Level Social Determinants of Health and Sepsis Incidence and Mortality: A Scoping Review.Critical care explorations · 2026Article
- Temporal trends in sepsis hospitalisations and mortality in Aotearoa New Zealand, 2000-2019: a population-based study.The Lancet regional health. Western Pacific · 2025Article
- Population Sepsis Incidence, Mortality, and Trends in Hong Kong Between 2009 and 2018 Using Clinical and Administrative Data.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Temporal trend and survival impact of infection source among patients with sepsis: a nationwide study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2020Article
- Factors associated with sepsis risk in immune-mediated inflammatory diseases receiving tumor necrosis factor inhibitors: a nationwide study.Therapeutic advances in musculoskeletal disease · 2020Article
- Incidence, trends, and outcomes of infection sites among hospitalizations of sepsis: A nationwide study.PloS one · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis is a life-threatening complication of infection. The incidence of sepsis is thought to be on the increase, but estimates making use of administrative data in the United States may be affected by administrative bias.
methodsWe studied the population-based incidence of sepsis in the Waikato region of New Zealand from 2007 to 2012 using
resultsBetween 2007 and 2012, 1643 patients met coding criteria for sepsis in our hospitals. Sixty-three percent of patients were 65 or over, 17% of cases were admitted to an intensive care unit, and the in-hospital and 1-year mortality with sepsis was 19% and 38%, respectively. Age-standardized rate ratios (ASRRs) demonstrated that sepsis was associated with male sex (ASRR 1.4; 95% confidence interval [CI], 1.23-1.59), Maori ethnicity (ASRR 3.22 compared with non-Maori; 95% CI, 2.85-3.65), study year (ASRR 1.62 comparing 2012 with 2008; 95% CI, 1.18-2.24), and socioeconomic deprivation (ASRR 1.72 comparing the highest with the lowest quintile of socioeconomic deprivation; 95% CI, 1.5-1.97). Multiorgan failure was present in approximately 20% of cases in all age groups. Intensive care unit admission rate fell from 30% amongst 25- to 34-year-olds to less than 10% amongst those aged 75 and over.
conclusionsIn a 9% sample of the New Zealand population, the incidence of sepsis increased by 62% over a 5-year period. Maori, elderly, and disadvantaged populations were most affected.
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