Evidence map›Paper›PMID 28948174›Full record

ReviewJournal of immunology research2017

Intestinal Dysbiosis and Rheumatoid Arthritis: A Link between Gut Microbiota and the Pathogenesis of Rheumatoid Arthritis.

Gabriel Horta-Baas, María Del Socorro Romero-Figueroa, Alvaro José Montiel-Jarquín, María Luisa Pizano-Zárate, Jaime García-Mena, Ninfa Ramírez-Durán

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06322784 (Effects of Dietary Fiber), which is not on this map. Cited by 168 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06322784 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of Dietary Fiber (Oat Bran) Intervention on Inflammation, Intestinal Flora, Disease Activity and Quality of Life in Patients With Rheumatoid Arthritis

TypeinterventionalSponsorShenzhen People's HospitalRan2022 to 2024Enrolled25ConditionsRheumatoid ArthritisArmsOat bran (dietary fiber)
3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 1 synthesis or guideline pooled it, 303 citations in OpenAlex.

  1. Pooled it
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  15. Nutrients · 2025
    Article
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  20. Biomolecules · 2025
    Article

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Gabriel Horta-BaasServicio de Reumatología, Hospital General Regional 220, Instituto Mexicano del Seguro Social, Toluca, MEX, Mexico.ORCID 0000-0001-5710-2137
María Del Socorro Romero-FigueroaCoordinación de Investigación en Salud, Delegación Estado de México Poniente, Instituto Mexicano del Seguro Social, Toluca, MEX, Mexico.ORCID 0000-0003-3556-815X
Alvaro José Montiel-JarquínJefatura de División de Investigación en Salud, Unidad Médica de Alta Especialidad Hospital de Traumatología y Ortopedia, Instituto Mexicano del Seguro Social, Puebla, PUE, Mexico.
María Luisa Pizano-ZárateDepartamento de Nutrición y Bioprogramación, Instituto Nacional de Perinatología, Secretaría de Salud, Ciudad de México, Mexico.
Jaime García-MenaDepartamento de Genética y Biología Molecular, Cinvestav, Av IPN 2508 Col Zacatenco, Ciudad de México, Mexico.ORCID 0000-0002-0595-3711
Ninfa Ramírez-DuránLaboratory of Medical and Environmental Microbiology, Department of Medicine, Autonomous University of the State of Mexico, Toluca, MEX, Mexico.ORCID 0000-0003-3108-895X
Mexican Social Security Institute · MXInstituto Nacional de Perinatología · MXInstituto Politécnico Nacional · MXUniversidad Autónoma del Estado de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterization and understanding of gut microbiota has recently increased representing a wide research field, especially in autoimmune diseases. Gut microbiota is the major source of microbes which might exert beneficial as well as pathogenic effects on human health. Intestinal microbiome's role as mediator of inflammation has only recently emerged. Microbiota has been observed to differ in subjects with early rheumatoid arthritis compared to controls, and this finding has commanded this study as a possible autoimmune process. Studies with intestinal microbiota have shown that rheumatoid arthritis is characterized by an expansion and/or decrease of bacterial groups as compared to controls. In this review, we present evidence linking intestinal dysbiosis with the autoimmune mechanisms involved in the development of rheumatoid arthritis.

Indexed as

AnimalsArthritis, RheumatoidAutoimmunityDysbiosisGastrointestinal MicrobiomeHumansInflammationIntestines

Identifiers

PMID28948174
PMCPMC5602494
OpenAlexW2751327994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.